Directing NGF's actions: It's a rap

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Epidermal growth factor and nerve growth factor (NGF) lead to significantly different temporal patterns of extracellular-signal-regulated kinase activation, and differential regulation of Ras and Rap1 have been implicated in mediating this temporal specificity. Now Sasagawa et al. derive a computational model that incorporates the known signalling interactions and identifies key points of regulation that control these processes.

Original languageEnglish (US)
Pages (from-to)338-339
Number of pages2
JournalNature Cell Biology
Issue number4
StatePublished - Apr 2005

ASJC Scopus subject areas

  • Cell Biology


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