Directed hybridization of DNA derivatized nanoparticles into higher order structures

Dietrich A. Dehlinger; Benjamin D. Sullivan; Sadik Esener; Michael J. Heller

doi:10.1021/nl802369b

Directed hybridization of DNA derivatized nanoparticles into higher order structures

Dietrich A. Dehlinger, Benjamin D. Sullivan, Sadik Esener, Michael J. Heller

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Electric field directed hybridization was used to produce twenty layer nanostructures composed of DNA derivatized nanoparticies. Using an electronic microarray device, DNA nanoparticles could be directed and concentrated such that rapid and specific hybridization occurs only on the activated sites. Nanoparticle layers were formed within 30 s of activation and twenty layer structures completed in under an hour. Results demonstrate a unique combination of bottom-up and top-down techniques for nanofabrication.

Original language	English (US)
Pages (from-to)	4053-4060
Number of pages	8
Journal	Nano Letters
Volume	8
Issue number	11
DOIs	https://doi.org/10.1021/nl802369b
State	Published - Nov 2008
Externally published	Yes

ASJC Scopus subject areas

Bioengineering
General Chemistry
General Materials Science
Condensed Matter Physics
Mechanical Engineering

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10.1021/nl802369b

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abstract = "Electric field directed hybridization was used to produce twenty layer nanostructures composed of DNA derivatized nanoparticies. Using an electronic microarray device, DNA nanoparticles could be directed and concentrated such that rapid and specific hybridization occurs only on the activated sites. Nanoparticle layers were formed within 30 s of activation and twenty layer structures completed in under an hour. Results demonstrate a unique combination of bottom-up and top-down techniques for nanofabrication.",

author = "Dehlinger, {Dietrich A.} and Sullivan, {Benjamin D.} and Sadik Esener and Heller, {Michael J.}",

year = "2008",

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AU - Dehlinger, Dietrich A.

AU - Sullivan, Benjamin D.

AU - Esener, Sadik

AU - Heller, Michael J.

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Y1 - 2008/11

N2 - Electric field directed hybridization was used to produce twenty layer nanostructures composed of DNA derivatized nanoparticies. Using an electronic microarray device, DNA nanoparticles could be directed and concentrated such that rapid and specific hybridization occurs only on the activated sites. Nanoparticle layers were formed within 30 s of activation and twenty layer structures completed in under an hour. Results demonstrate a unique combination of bottom-up and top-down techniques for nanofabrication.

AB - Electric field directed hybridization was used to produce twenty layer nanostructures composed of DNA derivatized nanoparticies. Using an electronic microarray device, DNA nanoparticles could be directed and concentrated such that rapid and specific hybridization occurs only on the activated sites. Nanoparticle layers were formed within 30 s of activation and twenty layer structures completed in under an hour. Results demonstrate a unique combination of bottom-up and top-down techniques for nanofabrication.

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Directed hybridization of DNA derivatized nanoparticles into higher order structures

Abstract

ASJC Scopus subject areas

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