TY - JOUR
T1 - Dimethylaminoethanol in Tardive Dyskinesia
AU - Casey, Daniel E.
AU - Denney, Duane
PY - 1974/10/10
Y1 - 1974/10/10
N2 - To the Editor: Tardive dyskinesia, associated with long-term neuroleptic therapy,1 warrants concern because of its occasionally persistent nature and unpredictable course, and the absence of a consistently effective treatment.2 The recent treatment of levodopa-induced dyskinesia with dimethylaminoethanol3 led to the successful therapeutic trial in the treatment of a case of severe neuroleptic-induced dyskinesia. A 59-year-old man complained of involuntary movements of the mouth and tongue, tremors of the hands and feet, inability to sit still, and restlessness while tapering the phenothiazine dosage after five years of 400 mg daily of chlorpromazine and 10 mg of trifluoperazine. Family history, physical examination, No extract is available for articles shorter than 400 words.
AB - To the Editor: Tardive dyskinesia, associated with long-term neuroleptic therapy,1 warrants concern because of its occasionally persistent nature and unpredictable course, and the absence of a consistently effective treatment.2 The recent treatment of levodopa-induced dyskinesia with dimethylaminoethanol3 led to the successful therapeutic trial in the treatment of a case of severe neuroleptic-induced dyskinesia. A 59-year-old man complained of involuntary movements of the mouth and tongue, tremors of the hands and feet, inability to sit still, and restlessness while tapering the phenothiazine dosage after five years of 400 mg daily of chlorpromazine and 10 mg of trifluoperazine. Family history, physical examination, No extract is available for articles shorter than 400 words.
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U2 - 10.1056/NEJM197410102911521
DO - 10.1056/NEJM197410102911521
M3 - Letter
C2 - 4414187
AN - SCOPUS:0016389472
SN - 0028-4793
VL - 291
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 15
ER -