Dim light melatonin onset and circadian temperature during a constant routine in hypersomnic winter depression

K. Dahl; D. H. Avery; A. J. Lewy; M. V. Savage; G. L. Brengelmann; L. H. Larsen; M. V. Vitiello; P. N. Prinz

doi:10.1111/j.1600-0447.1993.tb03414.x

Dim light melatonin onset and circadian temperature during a constant routine in hypersomnic winter depression

K. Dahl, D. H. Avery, A. J. Lewy, M. V. Savage, G. L. Brengelmann, L. H. Larsen, M. V. Vitiello, P. N. Prinz

Research output: Contribution to journal › Article › peer-review

91 Scopus citations

Abstract

The onset of melatonin secretion under dim light conditions (DLMO) and the circadian temperature rhythm during a constant routine were assessed in 6 female controls and 6 female patients with winter depression (seasonal affective disorder, SAD) before and after bright light treatment. After sleep was standardized for 6 days, the subjects were sleep‐deprived and at bedrest for 27 h while core temperature and evening melatonin levels were determined. The DLMO of the SAD patients was phase‐delayed compared with controls (2310 vs 2138); with bright light treatment, the DLMO advanced (2310 to 2135). The minimum of the fitted rectal temperature rhythm was phase‐delayed in the SAD group compared with the controls (0542 vs 0316); with bright light treatment, the minimum advanced (0542 vs 0336).

Original language	English (US)
Pages (from-to)	60-66
Number of pages	7
Journal	Acta Psychiatrica Scandinavica
Volume	88
Issue number	1
DOIs	https://doi.org/10.1111/j.1600-0447.1993.tb03414.x
State	Published - Jul 1993
Externally published	Yes

Keywords

circadian rhythm
light therapy
melatonin
seasonal affective disorder

ASJC Scopus subject areas

Psychiatry and Mental health

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10.1111/j.1600-0447.1993.tb03414.x

Cite this

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title = "Dim light melatonin onset and circadian temperature during a constant routine in hypersomnic winter depression",

abstract = "The onset of melatonin secretion under dim light conditions (DLMO) and the circadian temperature rhythm during a constant routine were assessed in 6 female controls and 6 female patients with winter depression (seasonal affective disorder, SAD) before and after bright light treatment. After sleep was standardized for 6 days, the subjects were sleep‐deprived and at bedrest for 27 h while core temperature and evening melatonin levels were determined. The DLMO of the SAD patients was phase‐delayed compared with controls (2310 vs 2138); with bright light treatment, the DLMO advanced (2310 to 2135). The minimum of the fitted rectal temperature rhythm was phase‐delayed in the SAD group compared with the controls (0542 vs 0316); with bright light treatment, the minimum advanced (0542 vs 0336).",

keywords = "circadian rhythm, light therapy, melatonin, seasonal affective disorder",

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AU - Dahl, K.

AU - Avery, D. H.

AU - Lewy, A. J.

AU - Savage, M. V.

AU - Brengelmann, G. L.

AU - Larsen, L. H.

AU - Vitiello, M. V.

AU - Prinz, P. N.

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N2 - The onset of melatonin secretion under dim light conditions (DLMO) and the circadian temperature rhythm during a constant routine were assessed in 6 female controls and 6 female patients with winter depression (seasonal affective disorder, SAD) before and after bright light treatment. After sleep was standardized for 6 days, the subjects were sleep‐deprived and at bedrest for 27 h while core temperature and evening melatonin levels were determined. The DLMO of the SAD patients was phase‐delayed compared with controls (2310 vs 2138); with bright light treatment, the DLMO advanced (2310 to 2135). The minimum of the fitted rectal temperature rhythm was phase‐delayed in the SAD group compared with the controls (0542 vs 0316); with bright light treatment, the minimum advanced (0542 vs 0336).

AB - The onset of melatonin secretion under dim light conditions (DLMO) and the circadian temperature rhythm during a constant routine were assessed in 6 female controls and 6 female patients with winter depression (seasonal affective disorder, SAD) before and after bright light treatment. After sleep was standardized for 6 days, the subjects were sleep‐deprived and at bedrest for 27 h while core temperature and evening melatonin levels were determined. The DLMO of the SAD patients was phase‐delayed compared with controls (2310 vs 2138); with bright light treatment, the DLMO advanced (2310 to 2135). The minimum of the fitted rectal temperature rhythm was phase‐delayed in the SAD group compared with the controls (0542 vs 0316); with bright light treatment, the minimum advanced (0542 vs 0336).

KW - circadian rhythm

KW - light therapy

KW - melatonin

KW - seasonal affective disorder

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Dim light melatonin onset and circadian temperature during a constant routine in hypersomnic winter depression

Abstract

Keywords

ASJC Scopus subject areas

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