Digital Subtraction Myocardial Contrast Echocardiography: Design and Application of a New Analysis Program for Myocardial Perfusion Imaging

Menachem Halmann, Rafael Beyar, Diana Rinkevich, Janine R. Shapiro, Samuel Sideman, Walter Markiewicz, Richard S. Meltzer, Shimon A. Reisner

    Research output: Contribution to journalArticle

    7 Scopus citations


    Myocardial contrast echocardiography may provide important physiologic information on myocardial perfusion. Most current analysis programs use manual frame grabbing and selecting of the area of interest. This is time-consuming and not highly reproducible. A system for automatic analysis of myocardial contrast echocardiographic studies was developed and evaluated. The program acquires an electrocardiographically gated sequence of end-diastolic images with a frame grabber in a personal computer. The baseline image is subtracted and the videodensity versus time contrast curve parameters are calculated on-line. Fast color-coded analysis is done automatically with a running square window that covers the entire image. A second mode of contrast analysis allows manual selection of multiple regions of interest. The program was evaluated with contrast echo data from open-chest dogs and two demonstrative patients. This myocardial contrast analytic package is an inexpensive, rapid, flexible, convenient, and reproducible on-line method that facilitates myocardial contrast echocardiographic analysis.

    Original languageEnglish (US)
    Pages (from-to)355-362
    Number of pages8
    JournalJournal of the American Society of Echocardiography
    Issue number4
    StatePublished - Jan 1 1994


    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging
    • Cardiology and Cardiovascular Medicine

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