Diffusion weighted magnetic resonance imaging of liver: Principles, clinical applications and recent updates

Anuradha Shenoy-Bhangle, Vinit Baliyan, Hamed Kordbacheh, Alexander R. Guimaraes, Avinash Kambadakone

Research output: Contribution to journalReview article

19 Scopus citations

Abstract

Diffusion-weighted imaging (DWI), a functional imaging technique exploiting the Brownian motion of water molecules, is increasingly shown to have value in various oncological and non-oncological applications. Factors such as the ease of acquisition and ability to obtain functional information in the absence of intravenous contrast, especially in patients with abnormal renal function, have contributed to the growing interest in exploring clinical applications of DWI. In the liver, DWI demonstrates a gamut of clinical applications ranging from detecting focal liver lesions to monitoring response in patients undergoing serial follow-up after loco-regional and systemic therapies. DWI is also being applied in the evaluation of diffuse liver diseases such as non-alcoholic fatty liver disease, hepatic fibrosis and cirrhosis. In this review, we intend to review the basic principles, technique, current clinical applications and future trends of DW-MRI in the liver.

Original languageEnglish (US)
Pages (from-to)1081-1091
Number of pages11
JournalWorld Journal of Hepatology
Volume9
Issue number26
DOIs
StatePublished - Sep 18 2017

Keywords

  • Diffuse liver disease
  • Diffusion weighted imaging
  • Focal liver lesion
  • Liver imaging
  • Magnetic resonance imaging
  • Response assessment

ASJC Scopus subject areas

  • Hepatology

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