Abstract
Abundant proliferation of cells having the histologic and tinctorial features of microglia, were seen in the brain of 34-year-old man who suffered cardiac arrest 10 days before death and whose bone marrow was nearly totally depleted of white-blood-cell precursors. It is suggested, that in adult human brains there are native microglial precursors which can take on a phagocytic function. Therefore, brain macrophages do not have to originate from circulating monocytes, as suggested by some animal studies.
Original language | English (US) |
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Pages (from-to) | 259-262 |
Number of pages | 4 |
Journal | Acta Neuropathologica |
Volume | 43 |
Issue number | 3 |
DOIs | |
State | Published - Jan 1978 |
Externally published | Yes |
Keywords
- Human brain inflammation
- Ischemia
- Microglia
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Clinical Neurology
- Cellular and Molecular Neuroscience