Abstract
Detection of blood vessels within light-scattering tissues involves detection of subtle shadows as blood absorbs light. These shadows are diffuse but measurable by a set of source-detector pairs in a spatial array of sources and detectors on the tissue surface. The measured shadows can reconstruct the internal position(s) of blood vessels. The tomographic method involves a set of Ns sources and Nd detectors such that Nsd = Ns x Nd source-detector pairs produce Nsd measurements, each interrogating the tissue with a unique perspective, i.e., a unique region of sensitivity to voxels within the tissue. This tutorial report describes the reconstruction of the image of a blood vessel within a soft tissue based on such source-detector measurements, by solving a matrix equation using Tikhonov regularization. This is not a novel contribution, but rather a simple introduction to a well-known method, demonstrating its use in mapping blood perfusion.
Original language | English (US) |
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Title of host publication | Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS) |
Publisher | SPIE |
Volume | 9917 |
ISBN (Electronic) | 9781510602267 |
DOIs | |
State | Published - 2016 |
Event | 3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015 - Saratov, Russian Federation Duration: Sep 22 2015 → Sep 25 2015 |
Other
Other | 3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015 |
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Country/Territory | Russian Federation |
City | Saratov |
Period | 9/22/15 → 9/25/15 |
Keywords
- Biomedical optic
- Diffuse light tomography
- Diffuse optic imaging
- Diffuse optical tomography
- Inverse problem solution
- Laser imaging
- Monte carlo simulation
- Tikhonov regularization
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging