Abstract
Detection of blood vessels within light-scattering tissues involves detection of subtle shadows as blood absorbs light. These shadows are diffuse but measurable by a set of source-detector pairs in a spatial array of sources and detectors on the tissue surface. The measured shadows can reconstruct the internal position(s) of blood vessels. The tomographic method involves a set of Ns sources and Nd detectors such that Nsd = Ns x Nd source-detector pairs produce Nsd measurements, each interrogating the tissue with a unique perspective, i.e., a unique region of sensitivity to voxels within the tissue. This tutorial report describes the reconstruction of the image of a blood vessel within a soft tissue based on such source-detector measurements, by solving a matrix equation using Tikhonov regularization. This is not a novel contribution, but rather a simple introduction to a well-known method, demonstrating its use in mapping blood perfusion.
| Original language | English (US) |
|---|---|
| Title of host publication | Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS) |
| Publisher | SPIE |
| Volume | 9917 |
| ISBN (Electronic) | 9781510602267 |
| DOIs | |
| State | Published - 2016 |
| Event | 3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015 - Saratov, Russian Federation Duration: Sep 22 2015 → Sep 25 2015 |
Other
| Other | 3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015 |
|---|---|
| Country | Russian Federation |
| City | Saratov |
| Period | 9/22/15 → 9/25/15 |
Fingerprint
Keywords
- Biomedical optic
- Diffuse light tomography
- Diffuse optic imaging
- Diffuse optical tomography
- Inverse problem solution
- Laser imaging
- Monte carlo simulation
- Tikhonov regularization
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging
Cite this
Diffuse light tomography to detect blood vessels using Tikhonov regularization. / Kazanci, Huseyin Ozgur; Jacques, Steven.
Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS). Vol. 9917 SPIE, 2016. 99170T.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Diffuse light tomography to detect blood vessels using Tikhonov regularization
AU - Kazanci, Huseyin Ozgur
AU - Jacques, Steven
PY - 2016
Y1 - 2016
N2 - Detection of blood vessels within light-scattering tissues involves detection of subtle shadows as blood absorbs light. These shadows are diffuse but measurable by a set of source-detector pairs in a spatial array of sources and detectors on the tissue surface. The measured shadows can reconstruct the internal position(s) of blood vessels. The tomographic method involves a set of Ns sources and Nd detectors such that Nsd = Ns x Nd source-detector pairs produce Nsd measurements, each interrogating the tissue with a unique perspective, i.e., a unique region of sensitivity to voxels within the tissue. This tutorial report describes the reconstruction of the image of a blood vessel within a soft tissue based on such source-detector measurements, by solving a matrix equation using Tikhonov regularization. This is not a novel contribution, but rather a simple introduction to a well-known method, demonstrating its use in mapping blood perfusion.
AB - Detection of blood vessels within light-scattering tissues involves detection of subtle shadows as blood absorbs light. These shadows are diffuse but measurable by a set of source-detector pairs in a spatial array of sources and detectors on the tissue surface. The measured shadows can reconstruct the internal position(s) of blood vessels. The tomographic method involves a set of Ns sources and Nd detectors such that Nsd = Ns x Nd source-detector pairs produce Nsd measurements, each interrogating the tissue with a unique perspective, i.e., a unique region of sensitivity to voxels within the tissue. This tutorial report describes the reconstruction of the image of a blood vessel within a soft tissue based on such source-detector measurements, by solving a matrix equation using Tikhonov regularization. This is not a novel contribution, but rather a simple introduction to a well-known method, demonstrating its use in mapping blood perfusion.
KW - Biomedical optic
KW - Diffuse light tomography
KW - Diffuse optic imaging
KW - Diffuse optical tomography
KW - Inverse problem solution
KW - Laser imaging
KW - Monte carlo simulation
KW - Tikhonov regularization
UR - http://www.scopus.com/inward/record.url?scp=84975090059&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84975090059&partnerID=8YFLogxK
U2 - 10.1117/12.2230074
DO - 10.1117/12.2230074
M3 - Conference contribution
AN - SCOPUS:84975090059
VL - 9917
BT - Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS)
PB - SPIE
ER -