Dietary calcium and blood pressure: Modifying factors in specific populations

David A. McCarron, Cynthia Morris, Eric Young, Chantai Roullet, Tilman Drüeke

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Epidemiologic findings continue to add to the body of evidence supporting a relationship between calcium intake and blood pressure. These findings also indicate that there is a threshold of the potential protective effect of adequate calcium intake, below which the risk of hypertension increases at a greater rate. The set point of this threshold, estimated at 700-800 mg/d, may be modified by a variety of factors including dietary patterns and components, lifestyle, and genetics. This may explain, at least in part, the heterogeneous response observed in dietary-intervention studies. In animal models of hypertension it was shown that greater amounts of calcium must be given to cause a blood pressure change comparable with that in normal animals, suggesting that in high-risk human populations in which calcium metabolism may be disordered, calcium intake may have to be increased to amounts > 700-800 mg/d to demonstrate the blood-pressure-lowering effect. Calcium intake at or above the currently recommended daily allowance of 800 mg could be of potential benefit to certain racial groups, individuals ingesting excessive alcohol, and pregnant women, all of whom generally consume low amounts of calcium and who are at higher risk of developing hypertension.

Original languageEnglish (US)
JournalAmerican Journal of Clinical Nutrition
Volume54
Issue numberSUPPL. 1
StatePublished - Jul 1991

Fingerprint

Dietary Calcium
blood pressure
Blood Pressure
Calcium
calcium
Population
hypertension
Hypertension
Recommended Dietary Allowances
pregnant women
eating habits
human population
lifestyle
protective effect
Life Style
Pregnant Women
alcohols
Animal Models
animal models
Alcohols

Keywords

  • Blood pressure
  • Dietary ca
  • Hypertension
  • Intestinal ca transport

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Dietary calcium and blood pressure : Modifying factors in specific populations. / McCarron, David A.; Morris, Cynthia; Young, Eric; Roullet, Chantai; Drüeke, Tilman.

In: American Journal of Clinical Nutrition, Vol. 54, No. SUPPL. 1, 07.1991.

Research output: Contribution to journalArticle

McCarron, David A. ; Morris, Cynthia ; Young, Eric ; Roullet, Chantai ; Drüeke, Tilman. / Dietary calcium and blood pressure : Modifying factors in specific populations. In: American Journal of Clinical Nutrition. 1991 ; Vol. 54, No. SUPPL. 1.
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