Diagnostic work-up for severe aplastic anemia in children: Consensus of the North American Pediatric Aplastic Anemia Consortium

Kristin A. Shimano, Anupama Narla, Melissa J. Rose, Nicholas J. Gloude, Steven W. Allen, Katie Bergstrom, Larisa Broglie, Beth A. Carella, Paul Castillo, Jill L.O. de Jong, Yigal Dror, Amy E. Geddis, James N. Huang, Bonnie W. Lau, Catherine McGuinn, Taizo A. Nakano, Kathleen Overholt, Jennifer A. Rothman, Anjali Sharathkumar, Evan ShereckAdrianna Vlachos, Timothy S. Olson, Alison A. Bertuch, Marcin W. Wlodarski, Akiko Shimamura, Jessica Boklan

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

The North American Pediatric Aplastic Anemia Consortium (NAPAAC) is a group of pediatric hematologist-oncologists, hematopathologists, and bone marrow transplant physicians from 46 institutions in North America with interest and expertise in aplastic anemia, inherited bone marrow failure syndromes, and myelodysplastic syndromes. The NAPAAC Bone Marrow Failure Diagnosis and Care Guidelines Working Group was established with the charge of harmonizing the approach to the diagnostic workup of aplastic anemia in an effort to standardize best practices in the field. This document outlines the rationale for initial evaluations in pediatric patients presenting with signs and symptoms concerning for severe aplastic anemia.

Original languageEnglish (US)
Pages (from-to)1491-1504
Number of pages14
JournalAmerican Journal of Hematology
Volume96
Issue number11
DOIs
StatePublished - Nov 1 2021

ASJC Scopus subject areas

  • Hematology

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