Diagnostic accuracy of image postprocessing methods for the detection of coronary artery stenoses by using multidetector CT

Maros Ferencik, Dieter Ropers, Suhny Abbara, Ricardo C. Cury, Udo Hoffmann, Koen Nieman, Thomas J. Brady, Fabian Moselewski, Werner G. Daniel, Stephan Achenbach

Research output: Contribution to journalArticle

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Abstract

Purpose: To retrospectively evaluate the diagnostic accuracy of multidetector computed tomography (CT) coronary angiography for detection of hemodynamically significant (≥50%) stenoses by using various image postprocessing methods, with conventional coronary angiography as the reference standard. Materials and Methods: The analysis used data from previous studies, use of which had been approved by the Institutional Review Board. Sixteen-section multidetector CT data sets for 40 patients (30 men, 10 women; mean age 56 years ± 8; mean heart rate, 61 beats per minute ± 6) were evaluated. Six independent investigators evaluated the data sets for the presence of stenoses with diameter reduction of 50% or more, by using either exclusively transverse images, free oblique multiplanar reconstructions (MPRs), free oblique maximum intensity projections (MIPs, 5 mm thick), prerendered curved MPRs, prerendered curved MIPs, or prerendered three-dimensional volume rendered reconstructions (VRTs). Evaluation results were compared with conventional coronary angiography for each artery in a blinded fashion (χ2 test). Results: Overall, 35 coronary artery stenoses were present. Percentage of evaluable arteries and accuracy for detecting stenosis (percentages of accurately classified arteries were, respectively, 99% and 88% for transverse, 99% and 91 % for oblique MPR, 94% and 86% for oblique MIP, 94% and 83% for curved MIP, 93% and 81% for curved MPR, and 91% and 73% for VRT). Accuracy was significantly higher for oblique MPR than for curved MPR (P = .01), curved MIP (P = .03), and VRT (P <.001). Conclusion: The evaluation of multidetector CT coronary angiography with interactive image display methods, especially interactive oblique MPRs, permits higher diagnostic accuracy than evaluation of prerendered images (curved MPR, curved MIP, or VRT images).

Original languageEnglish (US)
Pages (from-to)696-702
Number of pages7
JournalRadiology
Volume243
Issue number3
DOIs
StatePublished - Jun 2007
Externally publishedYes

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Multidetector Computed Tomography
Coronary Stenosis
Coronary Angiography
Pathologic Constriction
Arteries
Computer-Assisted Image Processing
Research Ethics Committees
Heart Rate
Research Personnel
Computed Tomography Angiography
Datasets

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

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Diagnostic accuracy of image postprocessing methods for the detection of coronary artery stenoses by using multidetector CT. / Ferencik, Maros; Ropers, Dieter; Abbara, Suhny; Cury, Ricardo C.; Hoffmann, Udo; Nieman, Koen; Brady, Thomas J.; Moselewski, Fabian; Daniel, Werner G.; Achenbach, Stephan.

In: Radiology, Vol. 243, No. 3, 06.2007, p. 696-702.

Research output: Contribution to journalArticle

Ferencik, M, Ropers, D, Abbara, S, Cury, RC, Hoffmann, U, Nieman, K, Brady, TJ, Moselewski, F, Daniel, WG & Achenbach, S 2007, 'Diagnostic accuracy of image postprocessing methods for the detection of coronary artery stenoses by using multidetector CT', Radiology, vol. 243, no. 3, pp. 696-702. https://doi.org/10.1148/radiol.2433060080
Ferencik, Maros ; Ropers, Dieter ; Abbara, Suhny ; Cury, Ricardo C. ; Hoffmann, Udo ; Nieman, Koen ; Brady, Thomas J. ; Moselewski, Fabian ; Daniel, Werner G. ; Achenbach, Stephan. / Diagnostic accuracy of image postprocessing methods for the detection of coronary artery stenoses by using multidetector CT. In: Radiology. 2007 ; Vol. 243, No. 3. pp. 696-702.
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abstract = "Purpose: To retrospectively evaluate the diagnostic accuracy of multidetector computed tomography (CT) coronary angiography for detection of hemodynamically significant (≥50{\%}) stenoses by using various image postprocessing methods, with conventional coronary angiography as the reference standard. Materials and Methods: The analysis used data from previous studies, use of which had been approved by the Institutional Review Board. Sixteen-section multidetector CT data sets for 40 patients (30 men, 10 women; mean age 56 years ± 8; mean heart rate, 61 beats per minute ± 6) were evaluated. Six independent investigators evaluated the data sets for the presence of stenoses with diameter reduction of 50{\%} or more, by using either exclusively transverse images, free oblique multiplanar reconstructions (MPRs), free oblique maximum intensity projections (MIPs, 5 mm thick), prerendered curved MPRs, prerendered curved MIPs, or prerendered three-dimensional volume rendered reconstructions (VRTs). Evaluation results were compared with conventional coronary angiography for each artery in a blinded fashion (χ2 test). Results: Overall, 35 coronary artery stenoses were present. Percentage of evaluable arteries and accuracy for detecting stenosis (percentages of accurately classified arteries were, respectively, 99{\%} and 88{\%} for transverse, 99{\%} and 91 {\%} for oblique MPR, 94{\%} and 86{\%} for oblique MIP, 94{\%} and 83{\%} for curved MIP, 93{\%} and 81{\%} for curved MPR, and 91{\%} and 73{\%} for VRT). Accuracy was significantly higher for oblique MPR than for curved MPR (P = .01), curved MIP (P = .03), and VRT (P <.001). Conclusion: The evaluation of multidetector CT coronary angiography with interactive image display methods, especially interactive oblique MPRs, permits higher diagnostic accuracy than evaluation of prerendered images (curved MPR, curved MIP, or VRT images).",
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T1 - Diagnostic accuracy of image postprocessing methods for the detection of coronary artery stenoses by using multidetector CT

AU - Ferencik, Maros

AU - Ropers, Dieter

AU - Abbara, Suhny

AU - Cury, Ricardo C.

AU - Hoffmann, Udo

AU - Nieman, Koen

AU - Brady, Thomas J.

AU - Moselewski, Fabian

AU - Daniel, Werner G.

AU - Achenbach, Stephan

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N2 - Purpose: To retrospectively evaluate the diagnostic accuracy of multidetector computed tomography (CT) coronary angiography for detection of hemodynamically significant (≥50%) stenoses by using various image postprocessing methods, with conventional coronary angiography as the reference standard. Materials and Methods: The analysis used data from previous studies, use of which had been approved by the Institutional Review Board. Sixteen-section multidetector CT data sets for 40 patients (30 men, 10 women; mean age 56 years ± 8; mean heart rate, 61 beats per minute ± 6) were evaluated. Six independent investigators evaluated the data sets for the presence of stenoses with diameter reduction of 50% or more, by using either exclusively transverse images, free oblique multiplanar reconstructions (MPRs), free oblique maximum intensity projections (MIPs, 5 mm thick), prerendered curved MPRs, prerendered curved MIPs, or prerendered three-dimensional volume rendered reconstructions (VRTs). Evaluation results were compared with conventional coronary angiography for each artery in a blinded fashion (χ2 test). Results: Overall, 35 coronary artery stenoses were present. Percentage of evaluable arteries and accuracy for detecting stenosis (percentages of accurately classified arteries were, respectively, 99% and 88% for transverse, 99% and 91 % for oblique MPR, 94% and 86% for oblique MIP, 94% and 83% for curved MIP, 93% and 81% for curved MPR, and 91% and 73% for VRT). Accuracy was significantly higher for oblique MPR than for curved MPR (P = .01), curved MIP (P = .03), and VRT (P <.001). Conclusion: The evaluation of multidetector CT coronary angiography with interactive image display methods, especially interactive oblique MPRs, permits higher diagnostic accuracy than evaluation of prerendered images (curved MPR, curved MIP, or VRT images).

AB - Purpose: To retrospectively evaluate the diagnostic accuracy of multidetector computed tomography (CT) coronary angiography for detection of hemodynamically significant (≥50%) stenoses by using various image postprocessing methods, with conventional coronary angiography as the reference standard. Materials and Methods: The analysis used data from previous studies, use of which had been approved by the Institutional Review Board. Sixteen-section multidetector CT data sets for 40 patients (30 men, 10 women; mean age 56 years ± 8; mean heart rate, 61 beats per minute ± 6) were evaluated. Six independent investigators evaluated the data sets for the presence of stenoses with diameter reduction of 50% or more, by using either exclusively transverse images, free oblique multiplanar reconstructions (MPRs), free oblique maximum intensity projections (MIPs, 5 mm thick), prerendered curved MPRs, prerendered curved MIPs, or prerendered three-dimensional volume rendered reconstructions (VRTs). Evaluation results were compared with conventional coronary angiography for each artery in a blinded fashion (χ2 test). Results: Overall, 35 coronary artery stenoses were present. Percentage of evaluable arteries and accuracy for detecting stenosis (percentages of accurately classified arteries were, respectively, 99% and 88% for transverse, 99% and 91 % for oblique MPR, 94% and 86% for oblique MIP, 94% and 83% for curved MIP, 93% and 81% for curved MPR, and 91% and 73% for VRT). Accuracy was significantly higher for oblique MPR than for curved MPR (P = .01), curved MIP (P = .03), and VRT (P <.001). Conclusion: The evaluation of multidetector CT coronary angiography with interactive image display methods, especially interactive oblique MPRs, permits higher diagnostic accuracy than evaluation of prerendered images (curved MPR, curved MIP, or VRT images).

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