TY - JOUR
T1 - Diagnosis of Alcoholic Liver Disease
T2 - Key Foundations and New Developments
AU - Childers, Ryan E.
AU - Ahn, Joseph
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Alcoholic liver disease is a spectrum of conditions that include alcoholic fatty liver disease, alcoholic hepatitis, and chronic alcoholic liver disease. The diagnosis of alcoholic liver disease remains founded in an accurate patient history and detailed physical examination. Concurrent with the physical examination, objective data from laboratory, imaging, and histologic studies are helpful to confirm a diagnosis of alcoholic liver disease. Novel biomarkers, scoring systems, and imaging modalities are improving the ability to diagnose and manage alcoholic liver disease, but for most practicing clinicians, these have not been adopted widely because of their cost, but also because of limitations and uncertainty in their performance characteristics.
AB - Alcoholic liver disease is a spectrum of conditions that include alcoholic fatty liver disease, alcoholic hepatitis, and chronic alcoholic liver disease. The diagnosis of alcoholic liver disease remains founded in an accurate patient history and detailed physical examination. Concurrent with the physical examination, objective data from laboratory, imaging, and histologic studies are helpful to confirm a diagnosis of alcoholic liver disease. Novel biomarkers, scoring systems, and imaging modalities are improving the ability to diagnose and manage alcoholic liver disease, but for most practicing clinicians, these have not been adopted widely because of their cost, but also because of limitations and uncertainty in their performance characteristics.
KW - Alcoholic fatty liver disease
KW - Alcoholic hepatitis
KW - Alcoholic liver disease
KW - Chronic alcoholic liver disease
KW - Cirrhosis
UR - http://www.scopus.com/inward/record.url?scp=84969594461&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84969594461&partnerID=8YFLogxK
U2 - 10.1016/j.cld.2016.02.005
DO - 10.1016/j.cld.2016.02.005
M3 - Review article
C2 - 27373609
AN - SCOPUS:84969594461
SN - 1089-3261
VL - 20
SP - 457
EP - 471
JO - Clinics in liver disease
JF - Clinics in liver disease
IS - 3
ER -