Diagnosis and management of noncardiac complications in adults with congenital heart disease: A scientific statement from the American Heart Association

American Heart Association Adult Congenital Heart Disease Committee, Council on Clinical Cardiology and Council on Cardiovascular Disease in the Young, Council on Cardiovascular Radiology and Intervention, Council on Quality of Care and Outcomes Research

Research output: Contribution to journalReview article

47 Scopus citations

Abstract

Life expectancy and quality of life for those born with congenital heart disease (CHD) have greatly improved over the past 3 decades. While representing a great advance for these patients, who have been able to move from childhood to successful adult lives in increasing numbers, this development has resulted in an epidemiological shift and a generation of patients who are at risk of developing chronic multisystem disease in adulthood. Noncardiac complications significantly contribute to the morbidity and mortality of adults with CHD. Reduced survival has been documented in patients with CHD with renal dysfunction, restrictive lung disease, anemia, and cirrhosis. Furthermore, as this population ages, atherosclerotic cardiovascular disease and its risk factors are becoming increasingly prevalent. Disorders of psychosocial and cognitive development are key factors affecting the quality of life of these individuals. It is incumbent on physicians who care for patients with CHD to be mindful of the effects that disease of organs other than the heart may have on the well-being of adults with CHD. Further research is needed to understand how these noncardiac complications may affect the long-term outcome in these patients and what modifiable factors can be targeted for preventive intervention.

Original languageEnglish (US)
Article numbere348-e392
JournalCirculation
Volume136
Issue number20
DOIs
StatePublished - Jan 1 2017

Keywords

  • AHA Scientific Statements
  • Control
  • Heart defects congenital
  • Heart diseases
  • Prevention

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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    American Heart Association Adult Congenital Heart Disease Committee, Council on Clinical Cardiology and Council on Cardiovascular Disease in the Young, Council on Cardiovascular Radiology and Intervention, & Council on Quality of Care and Outcomes Research (2017). Diagnosis and management of noncardiac complications in adults with congenital heart disease: A scientific statement from the American Heart Association. Circulation, 136(20), [e348-e392]. https://doi.org/10.1161/CIR.0000000000000535