Developmental prognosis for infants with benign enlargement of the subarachnoid spaces

Robert Nickel, J. S. Gallenstein

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

The development of nine infants with enlarged subarachnoid spaces identified by specific CT-scan criteria was prospectively followed to two to three years of age. Infants with intracranial hemorrhage, CNS anomaly, microcephaly or other factors of potentially major negative impact on their development were excluded. All study infants had normal or only minimally increased ventricular size and none developed hydrocephalus. Head circumference was ≥90th percentile in all cases, and six fathers also had a head circumference ≥90th percentile. Six infants had gross motor delay and mild hypotonia in the first year. One, born at 30 weeks gestational age, had transient dystonia. At follow-up all the infants were developing normally, apart from four with minor concerns. Infants with macrocephaly or rapid head-growth, CT-scan findings of enlarged subarachnoid spaces and normal to minimally increased ventricular size, and who have a parent with macrocephaly, have a good developmental prognosis and a characteristic pattern of neuromotor development in the first year.

Original languageEnglish (US)
Pages (from-to)181-186
Number of pages6
JournalDevelopmental Medicine and Child Neurology
Volume29
Issue number2
StatePublished - 1987

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Subarachnoid Space
Megalencephaly
Head
Microcephaly
Muscle Hypotonia
Dystonia
Intracranial Hemorrhages
Hydrocephalus
Child Development
Fathers
Gestational Age
Growth

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neuroscience(all)

Cite this

Developmental prognosis for infants with benign enlargement of the subarachnoid spaces. / Nickel, Robert; Gallenstein, J. S.

In: Developmental Medicine and Child Neurology, Vol. 29, No. 2, 1987, p. 181-186.

Research output: Contribution to journalArticle

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