Abstract
In the section of "Developmental Neurotoxicity: An Update" of the Pediatric Anesthesia Neurodevelopmental Assessment (PANDA) symposium 2018 the speakers presented the current literature in translational and clinical research. Dr. Brambrink spoke about translational research in anesthetic neurotoxicity, beginning with discovery in the rodent model, then focusing on evidence from nonhuman primates. Dr. Waspe applied the methodology of Adverse Outcome Pathways from the field of toxicology to developmental neurotoxicity of anesthetics. Dr. O'Leary presented relevant clinical studies that were published in 2017 divided by a focus on academic performance, clinical outcomes or diagnoses, or neuropsychological testing.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 108-114 |
| Number of pages | 7 |
| Journal | Journal of Neurosurgical Anesthesiology |
| Volume | 31 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2019 |
| Externally published | Yes |
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Keywords
- biomarkers
- clinical outcomes
- clinical research
- developmental neurotoxicity
- pathway
- translational research
ASJC Scopus subject areas
- Surgery
- Clinical Neurology
- Anesthesiology and Pain Medicine
Cite this
Developmental Neurotoxicity : An Update. / Houck, Philipp J.; Brambrink, Ansgar; Waspe, Jennifer; O'Leary, James D.; Ko, Riva.
In: Journal of Neurosurgical Anesthesiology, Vol. 31, No. 1, 01.01.2019, p. 108-114.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Developmental Neurotoxicity
T2 - An Update
AU - Houck, Philipp J.
AU - Brambrink, Ansgar
AU - Waspe, Jennifer
AU - O'Leary, James D.
AU - Ko, Riva
PY - 2019/1/1
Y1 - 2019/1/1
N2 - In the section of "Developmental Neurotoxicity: An Update" of the Pediatric Anesthesia Neurodevelopmental Assessment (PANDA) symposium 2018 the speakers presented the current literature in translational and clinical research. Dr. Brambrink spoke about translational research in anesthetic neurotoxicity, beginning with discovery in the rodent model, then focusing on evidence from nonhuman primates. Dr. Waspe applied the methodology of Adverse Outcome Pathways from the field of toxicology to developmental neurotoxicity of anesthetics. Dr. O'Leary presented relevant clinical studies that were published in 2017 divided by a focus on academic performance, clinical outcomes or diagnoses, or neuropsychological testing.
AB - In the section of "Developmental Neurotoxicity: An Update" of the Pediatric Anesthesia Neurodevelopmental Assessment (PANDA) symposium 2018 the speakers presented the current literature in translational and clinical research. Dr. Brambrink spoke about translational research in anesthetic neurotoxicity, beginning with discovery in the rodent model, then focusing on evidence from nonhuman primates. Dr. Waspe applied the methodology of Adverse Outcome Pathways from the field of toxicology to developmental neurotoxicity of anesthetics. Dr. O'Leary presented relevant clinical studies that were published in 2017 divided by a focus on academic performance, clinical outcomes or diagnoses, or neuropsychological testing.
KW - biomarkers
KW - clinical outcomes
KW - clinical research
KW - developmental neurotoxicity
KW - pathway
KW - translational research
UR - http://www.scopus.com/inward/record.url?scp=85058514441&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85058514441&partnerID=8YFLogxK
U2 - 10.1097/ANA.0000000000000557
DO - 10.1097/ANA.0000000000000557
M3 - Article
VL - 31
SP - 108
EP - 114
JO - Journal of Neurosurgical Anesthesiology
JF - Journal of Neurosurgical Anesthesiology
SN - 0898-4921
IS - 1
ER -