Developmental and Functional Effects of Steroid Hormones on the Neuroendocrine Axis and Spinal Cord

L. Zubeldia-Brenner, C. E. Roselli, S. E. Recabarren, M. C. Gonzalez Deniselle, H. E. Lara

Research output: Research - peer-reviewReview article

  • 2 Citations

Abstract

This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual orientation, reproductive and metabolic programming, and the neuroendocrine mechanism involved in the development of polycystic ovary syndrome phenotype. Moreover, consistent with the wide range of processes in which steroid hormones take part, we discuss the protective effects of progesterone on neurodegenerative disease and the signalling mechanism involved in the genesis of oestrogen-induced pituitary prolactinomas.

LanguageEnglish (US)
JournalJournal of Neuroendocrinology
Volume28
Issue number7
DOIs
StatePublished - Jul 1 2016

Fingerprint

Spinal Cord
Estrogens
Steroids
Hormones
Prolactinoma
Polycystic Ovary Syndrome
Sexual Behavior
Neurodegenerative Diseases
Progesterone
Testosterone
Phenotype

Keywords

  • androgens
  • hormonal programming
  • oestrogens
  • prolactin
  • steroid hormones

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Endocrine and Autonomic Systems
  • Cellular and Molecular Neuroscience

Cite this

Developmental and Functional Effects of Steroid Hormones on the Neuroendocrine Axis and Spinal Cord. / Zubeldia-Brenner, L.; Roselli, C. E.; Recabarren, S. E.; Gonzalez Deniselle, M. C.; Lara, H. E.

In: Journal of Neuroendocrinology, Vol. 28, No. 7, 01.07.2016.

Research output: Research - peer-reviewReview article

Zubeldia-Brenner L, Roselli CE, Recabarren SE, Gonzalez Deniselle MC, Lara HE. Developmental and Functional Effects of Steroid Hormones on the Neuroendocrine Axis and Spinal Cord. Journal of Neuroendocrinology. 2016 Jul 1;28(7). Available from, DOI: 10.1111/jne.12401
Zubeldia-Brenner, L. ; Roselli, C. E. ; Recabarren, S. E. ; Gonzalez Deniselle, M. C. ; Lara, H. E./ Developmental and Functional Effects of Steroid Hormones on the Neuroendocrine Axis and Spinal Cord. In: Journal of Neuroendocrinology. 2016 ; Vol. 28, No. 7.
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