Development of the peripheral glial cells in Drosophila

Marion Silies, Gundula Edenfeld, Daniel Engelen, Tobias Stork, Christian Klämbt

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

In complex organisms the nervous system comprises two cell types: neurons and glial cells. Their correct interplay is of crucial importance during both the development of the nervous system and for later function of the nervous system. In recent years tools have been developed for Drosophila that enable genetic approaches to understanding glial development and differentiation. Focusing on peripheral glial cells we first summarize wild-type development, then introduce some of the relevant genes that have been identified. Despite obvious differences between Drosophila and mammalian glial cells, the molecular machinery that controls terminal differentiation appears well conserved.

Original languageEnglish (US)
Pages (from-to)35-43
Number of pages9
JournalNeuron Glia Biology
Volume3
Issue number1
DOIs
StatePublished - Feb 1 2007

Keywords

  • Development
  • Drosophila
  • Glia

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • Cell Biology

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