TY - JOUR
T1 - Development and evaluation of the Seattle Angina questionnaire
T2 - A new functional status measure for coronary artery disease
AU - Spertus, John A.
AU - Winder, Jennifer A.
AU - Dewhurst, Timothy A.
AU - Deyo, Richard A.
AU - Prodzinski, Janice
AU - McDonnell, Mary
AU - Fihn, Stephan D.
N1 - Funding Information:
From the *Health Services Research and Development Program, Seattle Veterans Affairs Medical Center and TDepartments of Internal Medicine and Ca;&!ogy, University of Washington, Seattle, Washington. The research re-purted he*: was supported by HSR&D Project IIR 93-133R CSHS #1 from the Department of Veterans Affairs, Veterans Health Administration, Health Services Research and Development Service. Dr. Sperms was a Health Services Research and Development fellow at the Seattle Veterans Affairs Medical Center.
PY - 1995/2
Y1 - 1995/2
N2 - Objectives. This study sought to establish the validity, reproducibility and responsiveness of the Seattle Angina Questionnaire, a 19-item self-administered questionnaire measuring five dimensions of coronary artery disease: physical limitation, anginal stability, anginal frequency, treatment satisfaction and disease perception. Background. Assessing the functional status of patients is becoming increasingly important in both clinical research and quality assurance programs. No current functional status measure quantifies all of the important domains affected by coronary artery disease. Methods. Cross-sectional or serial administration of the Seattle Angina Questionnaire was carried out in four groups of patients: 70 undergoing exercise treadmil testing, 58 undergoing coronary angioplasty, 160 with initialty stable coronary artery disease and an additional 84 with coronary artery disease. Evidence of validity was sought by comparing the questionnaire's five scales with the duration of exercise treadmill tests, physicians diagnoses, nitroglycerin refills and other validated instruments. Reproducibility and responsiveness were assessed by comparing serial responses over a 3-month interval. Results. All five scales correlated significantly with other measures of diagnosis and patient function (r = 0.31 to 0.70, p ≤ 0.001). Questionnaire responses of patients with stable coronary artery disease did not change over 3 months. The questionnaire was sensitive to both dramatic clinical change, as seen after successful coronary angioplasty, and to more subtle-clinical change, as seen among outpatients with initially stable coronary artery disease. Conclusions. The Seattle Angina Questionnaire is a valid and reliable instrument that measures five clinically important dimensions of health in patients with coronary artery disease. It is sensitive to clinical change and should be a valuable measure of outcome in cardiovascular research.
AB - Objectives. This study sought to establish the validity, reproducibility and responsiveness of the Seattle Angina Questionnaire, a 19-item self-administered questionnaire measuring five dimensions of coronary artery disease: physical limitation, anginal stability, anginal frequency, treatment satisfaction and disease perception. Background. Assessing the functional status of patients is becoming increasingly important in both clinical research and quality assurance programs. No current functional status measure quantifies all of the important domains affected by coronary artery disease. Methods. Cross-sectional or serial administration of the Seattle Angina Questionnaire was carried out in four groups of patients: 70 undergoing exercise treadmil testing, 58 undergoing coronary angioplasty, 160 with initialty stable coronary artery disease and an additional 84 with coronary artery disease. Evidence of validity was sought by comparing the questionnaire's five scales with the duration of exercise treadmill tests, physicians diagnoses, nitroglycerin refills and other validated instruments. Reproducibility and responsiveness were assessed by comparing serial responses over a 3-month interval. Results. All five scales correlated significantly with other measures of diagnosis and patient function (r = 0.31 to 0.70, p ≤ 0.001). Questionnaire responses of patients with stable coronary artery disease did not change over 3 months. The questionnaire was sensitive to both dramatic clinical change, as seen after successful coronary angioplasty, and to more subtle-clinical change, as seen among outpatients with initially stable coronary artery disease. Conclusions. The Seattle Angina Questionnaire is a valid and reliable instrument that measures five clinically important dimensions of health in patients with coronary artery disease. It is sensitive to clinical change and should be a valuable measure of outcome in cardiovascular research.
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U2 - 10.1016/0735-1097(94)00397-9
DO - 10.1016/0735-1097(94)00397-9
M3 - Article
C2 - 7829785
AN - SCOPUS:0028877687
SN - 0735-1097
VL - 25
SP - 333
EP - 341
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 2
ER -