Detection of an object in a phantom tissue using a spatial filter

Dawn V. Stephens, Frank Tittel, Lihong Wang, Andreas Hielscher, Steve Jacques

Research output: Contribution to journalConference article

Abstract

We report the detection of an object inside a phantom tissue using a spatial filter and a 5 mW He-Ne Laser. The phantom tissue is composed of 8% scattering Polystyrene spheres (particle size 579 nm) and is diluted to different concentrations in water. The solution is placed inside of a cuvette of length 5 cm and width 5 cm. The spatial filter, composed of a 4 cm plano-convex lens and a 10 urn pinhole, is able to extract ballistic and quasi-ballistic photons from the transmitted light. A photomultiplier tube is used for detection, and a lock-in amplifier is used to reduce the amount of noise in the signal. We are able to detect the object in a phantom tissue of 20 mean free paths [mfp) (concentration .016%) with a contrast of 99.0%. The contrast in a tissue with 30 mfp (concentration .024%) is 22.7%.

Original languageEnglish (US)
Pages (from-to)200-208
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume2135
DOIs
StatePublished - May 19 1994
EventAdvances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases 1994 - Los Angeles, United States
Duration: Jan 23 1994Jan 29 1994

Fingerprint

Phantom
Ballistics
Tissue
Filter
filters
mean free path
ballistics
Path
Particle Size
Lens
Polystyrenes
Photomultipliers
Tube
Photon
photomultiplier tubes
pinholes
Scattering
Laser
Water
Lenses

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Detection of an object in a phantom tissue using a spatial filter. / Stephens, Dawn V.; Tittel, Frank; Wang, Lihong; Hielscher, Andreas; Jacques, Steve.

In: Proceedings of SPIE - The International Society for Optical Engineering, Vol. 2135, 19.05.1994, p. 200-208.

Research output: Contribution to journalConference article

Stephens, Dawn V. ; Tittel, Frank ; Wang, Lihong ; Hielscher, Andreas ; Jacques, Steve. / Detection of an object in a phantom tissue using a spatial filter. In: Proceedings of SPIE - The International Society for Optical Engineering. 1994 ; Vol. 2135. pp. 200-208.
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