Desired qualities and hypothetical contextual use of vaginal microbicides in a diverse sample of US women

Molly Lalor Olsen, Carrie A. Cwiak, Caroline Koudelka, Jeffrey T. Jensen

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Background: Vaginal microbicides represent an important emerging class of antiinfectives. To guide research and development, we conducted a survey to determine interest in desired qualities of and intended use of microbicides within the current milieu of contraceptive options. Study Design: Women completed an anonymous survey while waiting for health care clinic appointments in Portland, OR, and Atlanta, GA, and in one public area (Atlanta). Results: Four hundred one women completed the survey. Subjects had a mean age of 25.6 (SD=7.4), parity of 1.5 (SD=1.6) and 47.7% were non-Caucasian. Respondents showed moderate interest in noncontraceptive anti-HIV gel-based microbicides (mean, 53.8; SD, 39.6; n=362) and significantly stronger interest in contraceptive anti-HIV microbicides (mean, 89.4 mm; SD, 20.7; n=363; p<.001). The qualities of HIV, pregnancy and sexually transmitted infection (STI) prevention were the highest priorities of the largest percentage (40%) of respondents. Half (49.6%) of respondents reported they would use another form of protection in conjunction with a contraceptive anti-HIV microbicide. Conclusions: A diverse sample of women reported substantial interest in vaginal microbicides capable of preventing HIV and pregnancy, and a smaller high-risk subgroup was interested in noncontraceptive anti-HIV microbicides. Most women would prefer a product capable of preventing HIV, pregnancy and STIs. Almost half of respondents would use vaginal microbicides as part of a dual method.

Original languageEnglish (US)
Pages (from-to)314-318
Number of pages5
Issue number4
StatePublished - Oct 2007


  • Acceptability
  • Contraception
  • HIV
  • Sexually transmitted infection
  • Vaginal microbicide

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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