Design and profiling of GS-9148, a novel nucleotide analog active against nucleoside-resistant variants of human immunodeficiency virus type 1, and its orally bioavailable phosphonoamidate prodrug, GS-9131

Tomas Cihlar, Adrian S. Ray, Constantine G. Boojamra, Lijun Zhang, Hon Hui, Genevieve Laflamme, Jennifer E. Vela, Deborah Grant, James Chen, Florence Myrick, Kirsten L. White, Ying Gao, Kuei Ying Lin, Janet L. Douglas, Neil T. Parkin, Anne Carey, Rowchanak Pakdaman, Richard L. Mackman

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Medicine & Life Sciences