Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands

Nilesh Shah; Thomas S. Scanlan

doi:10.1016/j.bmcl.2004.07.052

Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands

Nilesh Shah, Thomas S. Scanlan

Physiology & Pharmacology

Research output: Contribution to journal › Article

76 Scopus citations

Abstract

A novel class of phenylpyrazole fused Wieland-Miescher ketone derivatives are high affinity, receptor specific, selective modulators of glucocorticoid receptor (GR) function.

Original language	English (US)
Pages (from-to)	5199-5203
Number of pages	5
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	14
Issue number	20
DOIs	https://doi.org/10.1016/j.bmcl.2004.07.052
State	Published - Oct 18 2004

Keywords

Glucocorticoid
Ligand
Nuclear receptor

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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Shah, N., & Scanlan, T. S. (2004). Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands. Bioorganic and Medicinal Chemistry Letters, 14(20), 5199-5203. https://doi.org/10.1016/j.bmcl.2004.07.052

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