Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands

Nilesh Shah, Thomas S. Scanlan

Research output: Contribution to journalArticle

76 Scopus citations

Abstract

A novel class of phenylpyrazole fused Wieland-Miescher ketone derivatives are high affinity, receptor specific, selective modulators of glucocorticoid receptor (GR) function.

Original languageEnglish (US)
Pages (from-to)5199-5203
Number of pages5
JournalBioorganic and Medicinal Chemistry Letters
Volume14
Issue number20
DOIs
StatePublished - Oct 18 2004

Keywords

  • Glucocorticoid
  • Ligand
  • Nuclear receptor

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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