Dermatomyositis as a presentation of neuromyelitis optica spectrum disorder

David Delman, Xianming Peng, Daniel C. Zedek, Valerie Jewells, Nizar Chahin, Silva Markovic-Plese

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Importance: This is the first report of neuromyelitis optica spectrum disorder (NMOSD) associated with dermatomyositis (DM). Report: A 40. year-old Caucasian female presented with 6. months of worsening fatigue, rash, acute weakness worse in her lower extremities, and urinary retention. She was found to have both NMOSD and anti-melanoma differentiation-associated gene (MDA)5 positive DM with interstitial lung disease (ILD). She was treated aggressively and she regained her ability to ambulate. Conclusion: We recommend considering NMOSD in the differential diagnosis of patients with DM and other autoimmune disorders that also present with clinical signs of myelopathy.

Original languageEnglish (US)
Pages (from-to)108-111
Number of pages4
JournalJournal of Neuroimmunology
Volume278
DOIs
StatePublished - Jan 15 2015
Externally publishedYes

Fingerprint

Neuromyelitis Optica
Dermatomyositis
Urinary Retention
Spinal Cord Diseases
Interstitial Lung Diseases
Exanthema
Fatigue
Lower Extremity
Melanoma
Differential Diagnosis
Genes

Keywords

  • Dermatomyositis
  • MDA5 antibody
  • Neuromyelitis optica

ASJC Scopus subject areas

  • Immunology
  • Clinical Neurology
  • Immunology and Allergy
  • Neurology
  • Medicine(all)

Cite this

Dermatomyositis as a presentation of neuromyelitis optica spectrum disorder. / Delman, David; Peng, Xianming; Zedek, Daniel C.; Jewells, Valerie; Chahin, Nizar; Markovic-Plese, Silva.

In: Journal of Neuroimmunology, Vol. 278, 15.01.2015, p. 108-111.

Research output: Contribution to journalArticle

Delman, David ; Peng, Xianming ; Zedek, Daniel C. ; Jewells, Valerie ; Chahin, Nizar ; Markovic-Plese, Silva. / Dermatomyositis as a presentation of neuromyelitis optica spectrum disorder. In: Journal of Neuroimmunology. 2015 ; Vol. 278. pp. 108-111.
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