Dermatomyositis as a presentation of neuromyelitis optica spectrum disorder

David Delman; Xianming Peng; Daniel C. Zedek; Valerie Jewells; Nizar Chahin; Silva Markovic-Plese

doi:10.1016/j.jneuroim.2014.07.016

Dermatomyositis as a presentation of neuromyelitis optica spectrum disorder

David Delman, Xianming Peng, Daniel C. Zedek, Valerie Jewells, Nizar Chahin, Silva Markovic-Plese

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Importance: This is the first report of neuromyelitis optica spectrum disorder (NMOSD) associated with dermatomyositis (DM). Report: A 40. year-old Caucasian female presented with 6. months of worsening fatigue, rash, acute weakness worse in her lower extremities, and urinary retention. She was found to have both NMOSD and anti-melanoma differentiation-associated gene (MDA)5 positive DM with interstitial lung disease (ILD). She was treated aggressively and she regained her ability to ambulate. Conclusion: We recommend considering NMOSD in the differential diagnosis of patients with DM and other autoimmune disorders that also present with clinical signs of myelopathy.

Original language	English (US)
Pages (from-to)	108-111
Number of pages	4
Journal	Journal of Neuroimmunology
Volume	278
DOIs	https://doi.org/10.1016/j.jneuroim.2014.07.016
State	Published - Jan 15 2015
Externally published	Yes

Keywords

Dermatomyositis
MDA5 antibody
Neuromyelitis optica

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Neurology
Clinical Neurology

Access to Document

10.1016/j.jneuroim.2014.07.016

Cite this

@article{4d3a56e0860944e4a43288908a6ec54c,

title = "Dermatomyositis as a presentation of neuromyelitis optica spectrum disorder",

abstract = "Importance: This is the first report of neuromyelitis optica spectrum disorder (NMOSD) associated with dermatomyositis (DM). Report: A 40. year-old Caucasian female presented with 6. months of worsening fatigue, rash, acute weakness worse in her lower extremities, and urinary retention. She was found to have both NMOSD and anti-melanoma differentiation-associated gene (MDA)5 positive DM with interstitial lung disease (ILD). She was treated aggressively and she regained her ability to ambulate. Conclusion: We recommend considering NMOSD in the differential diagnosis of patients with DM and other autoimmune disorders that also present with clinical signs of myelopathy.",

keywords = "Dermatomyositis, MDA5 antibody, Neuromyelitis optica",

author = "David Delman and Xianming Peng and Zedek, {Daniel C.} and Valerie Jewells and Nizar Chahin and Silva Markovic-Plese",

note = "Publisher Copyright: {\textcopyright} 2014 Elsevier B.V.",

year = "2015",

month = jan,

day = "15",

doi = "10.1016/j.jneuroim.2014.07.016",

language = "English (US)",

volume = "278",

pages = "108--111",

journal = "Journal of Neuroimmunology",

issn = "0165-5728",

publisher = "Elsevier",

}

TY - JOUR

T1 - Dermatomyositis as a presentation of neuromyelitis optica spectrum disorder

AU - Delman, David

AU - Peng, Xianming

AU - Zedek, Daniel C.

AU - Jewells, Valerie

AU - Chahin, Nizar

AU - Markovic-Plese, Silva

PY - 2015/1/15

Y1 - 2015/1/15

N2 - Importance: This is the first report of neuromyelitis optica spectrum disorder (NMOSD) associated with dermatomyositis (DM). Report: A 40. year-old Caucasian female presented with 6. months of worsening fatigue, rash, acute weakness worse in her lower extremities, and urinary retention. She was found to have both NMOSD and anti-melanoma differentiation-associated gene (MDA)5 positive DM with interstitial lung disease (ILD). She was treated aggressively and she regained her ability to ambulate. Conclusion: We recommend considering NMOSD in the differential diagnosis of patients with DM and other autoimmune disorders that also present with clinical signs of myelopathy.

AB - Importance: This is the first report of neuromyelitis optica spectrum disorder (NMOSD) associated with dermatomyositis (DM). Report: A 40. year-old Caucasian female presented with 6. months of worsening fatigue, rash, acute weakness worse in her lower extremities, and urinary retention. She was found to have both NMOSD and anti-melanoma differentiation-associated gene (MDA)5 positive DM with interstitial lung disease (ILD). She was treated aggressively and she regained her ability to ambulate. Conclusion: We recommend considering NMOSD in the differential diagnosis of patients with DM and other autoimmune disorders that also present with clinical signs of myelopathy.

KW - Dermatomyositis

KW - MDA5 antibody

KW - Neuromyelitis optica

UR - http://www.scopus.com/inward/record.url?scp=84920876979&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84920876979&partnerID=8YFLogxK

U2 - 10.1016/j.jneuroim.2014.07.016

DO - 10.1016/j.jneuroim.2014.07.016

M3 - Article

C2 - 25595259

AN - SCOPUS:84920876979

SN - 0165-5728

VL - 278

SP - 108

EP - 111

JO - Journal of Neuroimmunology

JF - Journal of Neuroimmunology

ER -

Dermatomyositis as a presentation of neuromyelitis optica spectrum disorder

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this