Dermatitis in a rhesus macaque (Macaca mulatta) experimentally infected with simian immunodeficiency virus

Jennifer Wilk, Anne Lewis, Victor Lukas

    Research output: Contribution to journalArticle

    4 Scopus citations

    Abstract

    Dermatopathies are common with human immunodeficiency virus (HIV) infection, affecting an estimated 90% of HIV patients. Opportunistic infections are common and include viral, bacterial and fungal etiologies. Dermal eruptions from highly active anti-retroviral therapy (HAART) or antibiotics such as trimethoprim-sulfamethoxazole (TMS) are also common, and can be challenging to differentiate from other causes of dermatitis. Presented is a challenging dermatology case involving a six year old male rhesus macaque experimentally infected with simian immunodeficiency virus (SIV). Skin cultures identified multi-antibiotic resistant Staphylococcus aureus, with incomplete resolution following appropriate antibiotic treatment. Skin biopsy results indicated non-specific dermatitis not consistent with typical SIV dermatitis and with a hypersensitivity component. Fungal culture revealed aspergillosis, and the patient responded favorably to oral itraconazole therapy.

    Original languageEnglish (US)
    Pages (from-to)25-28
    Number of pages4
    JournalJournal of medical primatology
    Volume37
    Issue numberSUPPL.1
    DOIs
    StatePublished - Feb 2008

    Keywords

    • Aspergillosis
    • Non-human primate
    • Skin

    ASJC Scopus subject areas

    • Animal Science and Zoology
    • veterinary(all)

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