Depression-specific outcomes after treatment of chronic rhinosinusitis

Rodney J. Schlosser, J. Madison Hyer, Timothy Smith, Jess C. Mace, Bernadette M. Cortese, Thomas W. Uhde, Luke Rudmik, Zachary M. Soler

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

IMPORTANCE: Depression is frequently undiagnosed in patients with chronic rhinosinusitis (CRS) and affects quality of life, productivity, and health care use. OBJECTIVE: To examine depression-specific outcomes after medical or surgical treatment of CRS. DESIGN, SETTING, AND PARTICIPANTS: A multi-institutional, prospective study of patients with refractory CRS treated at tertiary academic rhinology centers was performed from March 1, 2011, to November 1, 2015. Data analysis was performed from October 1, 2015, to November 1, 2015. INTERVENTIONS: Patients self-selected to undergo continued medical management or endoscopic sinus surgery for refractory CRS. MAIN OUTCOMES AND MEASURES: Patients completed the 22-item Sinonasal Outcome Test (SNOT22), Rhinosinusitis Disability Index (RSDI), Pittsburgh Sleep Quality Index (PSQI), and missed productivity and medication use questionnaires before and at least 6 months after treatment. Computed tomography and endoscopy scoring were performed with reviewers masked to patient-reported data. Depression-specific outcomes were recorded using the 2-item Patient Health Questionnaire (PHQ2). RESULTS: Baseline data were available on 685 patients, with 167 (24.4%) having depression according to the PHQ2 scores. The mean (SD) age of the patients was 50.5 (15.0) years, and 332 (48.4%) were male. Revision surgery status was the only baseline factor associated with depression (53.9% vs 38.0%, P

Original languageEnglish (US)
Pages (from-to)370-376
Number of pages7
JournalJAMA Otolaryngology - Head and Neck Surgery
Volume142
Issue number4
DOIs
StatePublished - Apr 1 2016

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Depression
Reoperation
Endoscopy
Sleep
Tomography
Quality of Life
Outcome Assessment (Health Care)
Prospective Studies
Delivery of Health Care
Health
Therapeutics
Surveys and Questionnaires

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery

Cite this

Schlosser, R. J., Hyer, J. M., Smith, T., Mace, J. C., Cortese, B. M., Uhde, T. W., ... Soler, Z. M. (2016). Depression-specific outcomes after treatment of chronic rhinosinusitis. JAMA Otolaryngology - Head and Neck Surgery, 142(4), 370-376. https://doi.org/10.1001/jamaoto.2015.3810

Depression-specific outcomes after treatment of chronic rhinosinusitis. / Schlosser, Rodney J.; Hyer, J. Madison; Smith, Timothy; Mace, Jess C.; Cortese, Bernadette M.; Uhde, Thomas W.; Rudmik, Luke; Soler, Zachary M.

In: JAMA Otolaryngology - Head and Neck Surgery, Vol. 142, No. 4, 01.04.2016, p. 370-376.

Research output: Contribution to journalArticle

Schlosser, RJ, Hyer, JM, Smith, T, Mace, JC, Cortese, BM, Uhde, TW, Rudmik, L & Soler, ZM 2016, 'Depression-specific outcomes after treatment of chronic rhinosinusitis', JAMA Otolaryngology - Head and Neck Surgery, vol. 142, no. 4, pp. 370-376. https://doi.org/10.1001/jamaoto.2015.3810
Schlosser, Rodney J. ; Hyer, J. Madison ; Smith, Timothy ; Mace, Jess C. ; Cortese, Bernadette M. ; Uhde, Thomas W. ; Rudmik, Luke ; Soler, Zachary M. / Depression-specific outcomes after treatment of chronic rhinosinusitis. In: JAMA Otolaryngology - Head and Neck Surgery. 2016 ; Vol. 142, No. 4. pp. 370-376.
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