TY - JOUR
T1 - Depression in patients being evaluated for heart transplantation
AU - Maricle, Robert A.
AU - Hosenpud, Jeffrey D.
AU - Norman, Douglas J.
AU - Woodbury, Ann
AU - Pantley, George A.
AU - Cobanoglu, Adnan M.
AU - Starr, Albert
PY - 1989/11
Y1 - 1989/11
N2 - In the evaluation of 68 consecutive heart transplant candidates, 37 (54%) had one or more depressive syndromes. Premorbid psychiatric risk factors of depression were prevalent throughout the group. Statistically significant associations with depression were found with age, educational and occupational levels, and a history of past depressive episodes, but not with family psychiatric history, parental loss in childhood, history of serious childhood illness, or history of substance abuse. Of the 43 patients transplanted, 16 of 22 who were depressed preoperatively required psychiatric intervention postoperatively compared to 8 of 21 who were not depressed; 75% had a beneficial response to treatment. We recommend that a diagnosis of depression not be considered reason to exclude otherwise suitable candidates for cardiac transplantation.
AB - In the evaluation of 68 consecutive heart transplant candidates, 37 (54%) had one or more depressive syndromes. Premorbid psychiatric risk factors of depression were prevalent throughout the group. Statistically significant associations with depression were found with age, educational and occupational levels, and a history of past depressive episodes, but not with family psychiatric history, parental loss in childhood, history of serious childhood illness, or history of substance abuse. Of the 43 patients transplanted, 16 of 22 who were depressed preoperatively required psychiatric intervention postoperatively compared to 8 of 21 who were not depressed; 75% had a beneficial response to treatment. We recommend that a diagnosis of depression not be considered reason to exclude otherwise suitable candidates for cardiac transplantation.
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U2 - 10.1016/0163-8343(89)90137-0
DO - 10.1016/0163-8343(89)90137-0
M3 - Article
C2 - 2806892
AN - SCOPUS:0024446559
SN - 0163-8343
VL - 11
SP - 418
EP - 424
JO - General Hospital Psychiatry
JF - General Hospital Psychiatry
IS - 6
ER -