Degree of angle closure and extent of peripheral anterior synechiae: An anterior segment OCT study

D. H W Su, D. S. Friedman, J. L S See, P. T K Chew, Y. H. Chan, W. P. Nolan, S. D. Smith, David Huang, C. Zheng, Yan Li, P. J. Foster, T. Aung

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Aims: To evaluate the relationship between angle width as determined by anterior segment optical coherence tomography (AS-OCT) and the presence of peripheral anterior synechiae (PAS). Methods: This was a prospective observational case series in which 203 subjects with primary angle closure or open angles were recruited. Images of the nasal, temporal and inferior angles were obtained with AS-OCT in dark conditions. Subjects then underwent gonioscopy by an independent examiner who was masked to the AS-OCT findings. PAS were identified by gonioscopy and defined as abnormal adhesions of the iris to the angle that were at least half a clock hour in width and present to the level of the anterior trabecular meshwork or higher. The total clock hours of PAS were recorded. Results: Sixty-eight subjects (33.5%) were PACS, 76 subjects (37.4%) had PAC/PACG, 14 (6.9%) had primary open angle glaucoma, and 45 (22.2%) subjects were normal with open angles. There was a weak but significant correlation between the angle opening distance (AOD), trabecular iris space area (TISA) and angle recess area (ARA) with clock hours of PAS (Spearman's correlation coefficients = -0.30, -0.32 and -0.32, respectively, p

Original languageEnglish (US)
Pages (from-to)103-107
Number of pages5
JournalBritish Journal of Ophthalmology
Volume92
Issue number1
DOIs
StatePublished - Jan 2008
Externally publishedYes

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Optical Coherence Tomography
Gonioscopy
Iris
Trabecular Meshwork
Nose

ASJC Scopus subject areas

  • Ophthalmology
  • Medicine(all)

Cite this

Su, D. H. W., Friedman, D. S., See, J. L. S., Chew, P. T. K., Chan, Y. H., Nolan, W. P., ... Aung, T. (2008). Degree of angle closure and extent of peripheral anterior synechiae: An anterior segment OCT study. British Journal of Ophthalmology, 92(1), 103-107. https://doi.org/10.1136/bjo.2007.122572

Degree of angle closure and extent of peripheral anterior synechiae : An anterior segment OCT study. / Su, D. H W; Friedman, D. S.; See, J. L S; Chew, P. T K; Chan, Y. H.; Nolan, W. P.; Smith, S. D.; Huang, David; Zheng, C.; Li, Yan; Foster, P. J.; Aung, T.

In: British Journal of Ophthalmology, Vol. 92, No. 1, 01.2008, p. 103-107.

Research output: Contribution to journalArticle

Su, DHW, Friedman, DS, See, JLS, Chew, PTK, Chan, YH, Nolan, WP, Smith, SD, Huang, D, Zheng, C, Li, Y, Foster, PJ & Aung, T 2008, 'Degree of angle closure and extent of peripheral anterior synechiae: An anterior segment OCT study', British Journal of Ophthalmology, vol. 92, no. 1, pp. 103-107. https://doi.org/10.1136/bjo.2007.122572
Su, D. H W ; Friedman, D. S. ; See, J. L S ; Chew, P. T K ; Chan, Y. H. ; Nolan, W. P. ; Smith, S. D. ; Huang, David ; Zheng, C. ; Li, Yan ; Foster, P. J. ; Aung, T. / Degree of angle closure and extent of peripheral anterior synechiae : An anterior segment OCT study. In: British Journal of Ophthalmology. 2008 ; Vol. 92, No. 1. pp. 103-107.
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