Deep vein thrombosis treated with streptokinase or heparin

a randomized study

A. J. Seaman, H. H. Common, Josef Rosch, C. T. Dotter, J. M. Porter, T. D. Lindell, W. L. Lawler, W. J. Schlueter

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Randomly assigned streptokinase or heparin therapy was studied in 50 patients with deep vein thrombosis of less than 2 weeks' duration. Venography was performed prior to therapy, after 3 days, and after 10 days. Two radiologists who were unaware of the patient's therapy compiled a single average lytic score for each patient at each time interval. Lysis of venous thrombi was significantly greater with streptokinase than with heparin after 3 days, but not after 10 days of treatment. Lytic scores achieved with streptokinase were significantly better than those achieved with heparin therapy (P

Original languageEnglish (US)
Pages (from-to)549-556
Number of pages8
JournalAngiology
Volume27
Issue number10
StatePublished - 1976

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Streptokinase
Venous Thrombosis
Heparin
Therapeutics
Phlebography
Thrombosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Seaman, A. J., Common, H. H., Rosch, J., Dotter, C. T., Porter, J. M., Lindell, T. D., ... Schlueter, W. J. (1976). Deep vein thrombosis treated with streptokinase or heparin: a randomized study. Angiology, 27(10), 549-556.

Deep vein thrombosis treated with streptokinase or heparin : a randomized study. / Seaman, A. J.; Common, H. H.; Rosch, Josef; Dotter, C. T.; Porter, J. M.; Lindell, T. D.; Lawler, W. L.; Schlueter, W. J.

In: Angiology, Vol. 27, No. 10, 1976, p. 549-556.

Research output: Contribution to journalArticle

Seaman, AJ, Common, HH, Rosch, J, Dotter, CT, Porter, JM, Lindell, TD, Lawler, WL & Schlueter, WJ 1976, 'Deep vein thrombosis treated with streptokinase or heparin: a randomized study', Angiology, vol. 27, no. 10, pp. 549-556.
Seaman AJ, Common HH, Rosch J, Dotter CT, Porter JM, Lindell TD et al. Deep vein thrombosis treated with streptokinase or heparin: a randomized study. Angiology. 1976;27(10):549-556.
Seaman, A. J. ; Common, H. H. ; Rosch, Josef ; Dotter, C. T. ; Porter, J. M. ; Lindell, T. D. ; Lawler, W. L. ; Schlueter, W. J. / Deep vein thrombosis treated with streptokinase or heparin : a randomized study. In: Angiology. 1976 ; Vol. 27, No. 10. pp. 549-556.
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