De novo isodicentric X chromosome

46,X,idic(X)(q24), and summary of literature

Anne Tsai, Catherine A. Fine, Michael Yang, Carol S. Walton, Linda Beischel, John P. Johnson

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We describe a 12-year-old patient, the second live born prenatally ascertained patient in the literature, with a de novo isodicentric X chromosome, karyotype 46,X,idic(X)(q24), with normal growth and development and lack of dysmorphic features. Molecular and cytogenetic studies were performed to further characterize the isodicentric chromosome X behavior. Literature on isodicentric X chromosomes with various breakpoints on Xq is reviewed and summarized.

Original languageEnglish (US)
Pages (from-to)923-930
Number of pages8
JournalAmerican Journal of Medical Genetics
Volume140 A
Issue number8
DOIs
StatePublished - Apr 15 2006
Externally publishedYes

Fingerprint

X Chromosome
Karyotype
Growth and Development
Cytogenetics

Keywords

  • Breakpoint on Xq
  • idic(X)(q24)
  • Isodicentric X chromosome

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Tsai, A., Fine, C. A., Yang, M., Walton, C. S., Beischel, L., & Johnson, J. P. (2006). De novo isodicentric X chromosome: 46,X,idic(X)(q24), and summary of literature. American Journal of Medical Genetics, 140 A(8), 923-930. https://doi.org/10.1002/ajmg.a.31184

De novo isodicentric X chromosome : 46,X,idic(X)(q24), and summary of literature. / Tsai, Anne; Fine, Catherine A.; Yang, Michael; Walton, Carol S.; Beischel, Linda; Johnson, John P.

In: American Journal of Medical Genetics, Vol. 140 A, No. 8, 15.04.2006, p. 923-930.

Research output: Contribution to journalArticle

Tsai, A, Fine, CA, Yang, M, Walton, CS, Beischel, L & Johnson, JP 2006, 'De novo isodicentric X chromosome: 46,X,idic(X)(q24), and summary of literature', American Journal of Medical Genetics, vol. 140 A, no. 8, pp. 923-930. https://doi.org/10.1002/ajmg.a.31184
Tsai, Anne ; Fine, Catherine A. ; Yang, Michael ; Walton, Carol S. ; Beischel, Linda ; Johnson, John P. / De novo isodicentric X chromosome : 46,X,idic(X)(q24), and summary of literature. In: American Journal of Medical Genetics. 2006 ; Vol. 140 A, No. 8. pp. 923-930.
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