Dancing with the host: Flow-dependent bacterial adhesion

Ralph R. Isberg, Penelope Barnes

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Most bacteria that colonize eukaryotes must bind directly to host cells to establish a replicative niche. In enteric bacteria, adhesion to host cells is often promoted by a lectin found on surface-localized pili. Some pili promote efficient adhesion only when they are subjected to shear stress, as found during the flow of blood over endothelium or mucous over the surface of the epithelium.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalCell
Volume110
Issue number1
DOIs
StatePublished - Jul 12 2002
Externally publishedYes

Fingerprint

Bacterial Adhesion
Bacteria
Adhesion
Enterobacteriaceae
Eukaryota
Lectins
Endothelium
Shear stress
Blood
Epithelium

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Dancing with the host : Flow-dependent bacterial adhesion. / Isberg, Ralph R.; Barnes, Penelope.

In: Cell, Vol. 110, No. 1, 12.07.2002, p. 1-4.

Research output: Contribution to journalArticle

Isberg, Ralph R. ; Barnes, Penelope. / Dancing with the host : Flow-dependent bacterial adhesion. In: Cell. 2002 ; Vol. 110, No. 1. pp. 1-4.
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