DADOS-Prospective

An open source application for Web-based prospective data collection

Lam Nguyen, Anand Shah, Matthew Harker, Henrique Martins, Mariana McCready, Andreia Menezes, Danny Jacobs, Ricardo Pietrobon

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: Randomized, prospective trials involving multi-institutional collaboration have become a central part of clinical and translational research. However, data management and coordination of multi-center studies is a complex process that involves developing systems for data collection and quality control, tracking data queries and resolutions, as well as developing communication procedures. We describe DADOS-Prospective, an open-source Web-based application for collecting and managing prospective data on human subjects for clinical and translational trials. DADOS-Prospective not only permits users to create new clinical research forms (CRF) and supports electronic signatures, but also offers the advantage of containing, in a single environment, raw research data in downloadable spreadsheet format, source documentation and regulatory files stored in PDF format, and audit trails. Results: Feedback from formal and field usability tests was used to guide the design and development of DADOS-Prospective. To date, DADOS-Prospective has been implemented in five prospective clinical studies at our institution. Four of these studies are still in the CRF creation phase and one study has been entirely launched. Conclusion: DADOS-Prospective has significant advantages over existing Web-based data collecting programs. At our institution, it has been demonstrated to be an efficient tool for prospective clinical studies.

Original languageEnglish (US)
Article number7
JournalSource Code for Biology and Medicine
Volume1
DOIs
StatePublished - Nov 13 2006
Externally publishedYes

Fingerprint

Research
Prospective Studies
Translational Medical Research
Quality Control
Documentation
Spreadsheets
Communication
Clinical Trials
Information management
Quality control
Feedback
Web-based
Open source
Data collection
Clinical Studies
Data Accuracy
Clinical research

ASJC Scopus subject areas

  • Information Systems
  • Computer Science Applications
  • Health Informatics
  • Information Systems and Management

Cite this

Nguyen, L., Shah, A., Harker, M., Martins, H., McCready, M., Menezes, A., ... Pietrobon, R. (2006). DADOS-Prospective: An open source application for Web-based prospective data collection. Source Code for Biology and Medicine, 1, [7]. https://doi.org/10.1186/1751-0473-1-7

DADOS-Prospective : An open source application for Web-based prospective data collection. / Nguyen, Lam; Shah, Anand; Harker, Matthew; Martins, Henrique; McCready, Mariana; Menezes, Andreia; Jacobs, Danny; Pietrobon, Ricardo.

In: Source Code for Biology and Medicine, Vol. 1, 7, 13.11.2006.

Research output: Contribution to journalArticle

Nguyen, Lam ; Shah, Anand ; Harker, Matthew ; Martins, Henrique ; McCready, Mariana ; Menezes, Andreia ; Jacobs, Danny ; Pietrobon, Ricardo. / DADOS-Prospective : An open source application for Web-based prospective data collection. In: Source Code for Biology and Medicine. 2006 ; Vol. 1.
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