Cytogenetic analysis of a hemosiderotic fibrolipomatous tumor

George R. Wettach, Luke J. Boyd, Helen J. Lawce, R. Ellen Magenis, Atiya Mansoor

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

Hemosiderotic fibrolipomatous tumor is an extremely rare, nonencapsulated, fatty lesion with a consistent histologic appearance that was originally considered reactive in nature. To our knowledge, there are no previous reports on the cytogenetics of this lesion. Reported here is a case of hemosiderotic fibrolipomatous tumor arising within the subcutaneous tissue of the right foot, dorsal aspect, of an otherwise healthy 35-year-old woman. Subsequent cytogenetic analysis revealed a clonal reciprocal translocation between chromosomes 1 and 10, with a further rearrangement involving this derivative chromosome 1 and chromosome 3. This, in addition to its characteristic morphology and immunophenotype, supports the neoplastic nature of this tumor and may aid in its diagnosis.

Original languageEnglish (US)
Pages (from-to)140-143
Number of pages4
JournalCancer Genetics and Cytogenetics
Volume182
Issue number2
DOIs
StatePublished - Apr 15 2008

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

Fingerprint Dive into the research topics of 'Cytogenetic analysis of a hemosiderotic fibrolipomatous tumor'. Together they form a unique fingerprint.

  • Cite this

    Wettach, G. R., Boyd, L. J., Lawce, H. J., Magenis, R. E., & Mansoor, A. (2008). Cytogenetic analysis of a hemosiderotic fibrolipomatous tumor. Cancer Genetics and Cytogenetics, 182(2), 140-143. https://doi.org/10.1016/j.cancergencyto.2008.01.012