Cytogenetic analysis of a hemosiderotic fibrolipomatous tumor

George R. Wettach, Luke J. Boyd, Helen J. Lawce, R. Ellen Magenis, Atiya Mansoor

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Hemosiderotic fibrolipomatous tumor is an extremely rare, nonencapsulated, fatty lesion with a consistent histologic appearance that was originally considered reactive in nature. To our knowledge, there are no previous reports on the cytogenetics of this lesion. Reported here is a case of hemosiderotic fibrolipomatous tumor arising within the subcutaneous tissue of the right foot, dorsal aspect, of an otherwise healthy 35-year-old woman. Subsequent cytogenetic analysis revealed a clonal reciprocal translocation between chromosomes 1 and 10, with a further rearrangement involving this derivative chromosome 1 and chromosome 3. This, in addition to its characteristic morphology and immunophenotype, supports the neoplastic nature of this tumor and may aid in its diagnosis.

Original languageEnglish (US)
Pages (from-to)140-143
Number of pages4
JournalCancer Genetics and Cytogenetics
Issue number2
StatePublished - Apr 15 2008

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research


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