Cytoarchitecture and saccular innervation of nucleus Y in the mouse

Christopher J. Frederickson, Dennis R. Trune

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

The cytoarchitecture and saccular innervation of the mouse nucleus y were investigated by using Golgi, Nissl, and myelin stains and anterograde axonal transport of horseradish peroxidase. Nucleus y was found to be a compact group of cells in a small fiber‐free region dorsal to the restiform body. Qualitative and morphometric analyses showed that most (75%) of the nucleus y neurons could not be reliably subdivided into morphologic subgroups, but varied continuously in soma size (15–25 μm), shape (fusiform to stellate), and number of dendrites (two to four), and had sparsely branched dendrites with an average of 3 to 4 spines per 10 μm of length. Three groups of cells that were identified morphometrically accounted for 10% (type I: large stellate cells), 9% (type II: long‐dendrite cells), and 6% (type III: elongated soma cells) of the y neurons. Vestibular nerve axons transporting horseradish peroxidase after injury at their origin in the saccular neuroepithelium were found to form a dense terminal meshwork that was virtually co‐extensive with the cytoarchitectonic boundaries of nucleus y. Nucleus y was distinguished from the overlying infracerebellar nucleus on the basis of anatomical, cytoarchitectural, and hodological features.

Original languageEnglish (US)
Pages (from-to)302-322
Number of pages21
JournalJournal of Comparative Neurology
Volume252
Issue number3
DOIs
StatePublished - Oct 15 1986

Keywords

  • Golgi
  • HRP
  • morphometrics
  • otolithic organ
  • vestibular nuclei

ASJC Scopus subject areas

  • Neuroscience(all)

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