Cystic periventricular leukomalacia and type of cerebral palsy in preterm infants

Brian Rogers, M. Msall, T. Owens, K. Guernsey, A. Brody, G. Buck, M. Hudak

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

A case series design was used to identity cases of cystic periventricular leukomalacia (N = 31) identified by neurosonography at one regional tertiary intensive care nursery. Patients were preterm infants born at ≥32 weeks of gestation who had cysts involving predominantly the middle-posterior or posterior-periventricular regions. Neurodevelopmental evaluations were made for 26 (96%) of 27 survivors. All infants assessed had cerebral palsy (i.e., 54% quadriplegia, 42% diplegia, and 4% hemiplegia). Most cognitive delays and all sensory impairments occurred in children with quadriplegia. Periventricular cysts were most extensive on parasagittal, anteroposterior views. The parasagittal, anteroposterior extent of periventricular cysts was most accurate in predicting the type and severity of motor and cognitive disabilities. Quadriplegia was associated with larger and more extensive cysts.

Original languageEnglish (US)
JournalJournal of Pediatrics
Volume125
Issue number1
DOIs
StatePublished - 1994
Externally publishedYes

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Periventricular Leukomalacia
Cerebral Palsy
Premature Infants
Quadriplegia
Cysts
Hemiplegia
Nurseries
Tertiary Healthcare
Critical Care
Survivors
Pregnancy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Cystic periventricular leukomalacia and type of cerebral palsy in preterm infants. / Rogers, Brian; Msall, M.; Owens, T.; Guernsey, K.; Brody, A.; Buck, G.; Hudak, M.

In: Journal of Pediatrics, Vol. 125, No. 1, 1994.

Research output: Contribution to journalArticle

Rogers, Brian ; Msall, M. ; Owens, T. ; Guernsey, K. ; Brody, A. ; Buck, G. ; Hudak, M. / Cystic periventricular leukomalacia and type of cerebral palsy in preterm infants. In: Journal of Pediatrics. 1994 ; Vol. 125, No. 1.
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