Cystic fibrosis transmembrane conductance regulator (CFTR) potentiators protect G551D but not Δf508 CFTR from thermal instability

Medicine & Life Sciences

• Cystic Fibrosis Transmembrane Conductance Regulator 100%
• Hot Temperature 61%
• ivacaftor 41%
• Mutation 10%
• Chloride Channels 7%
• Phenotype 7%
• Protein Transport 6%
• Homozygote 6%
• Amino Acid Substitution 6%
• Xenopus 6%
• Body Temperature 6%
• Cystic Fibrosis 5%
• Human Body 5%
• Oocytes 5%
• In Vitro Techniques 5%
• Aptitude 4%
• Clinical Trials 3%
• Lung 3%

Chemical Compounds

• Ivacaftor 25%
• Mutation 15%
• Thermal Stability 8%
• Reflection 4%
• Substitution Reaction 3%
• Protein 2%
• Acid 2%
• Molecule 2%