Cycad β-N-methylamino-L-alanine (BMAA), methylazoxymethanol, genotoxicity, and neurodegeneration

Peter Spencer, Valerie Palmer, Glen E. Kisby

Research output: Contribution to journalLetter

1 Citation (Scopus)

Abstract

Cycad-associated neurodegenerative disease is more strongly correlated with the gymnosperm's major neurotoxin cycasin (methylazoxymethanol glucoside) than with the minor neurotoxin β-N-methylamino-L-alanine (L-BMAA).

Original languageEnglish (US)
Pages (from-to)49-50
Number of pages2
JournalToxicon
Volume155
DOIs
StatePublished - Dec 1 2018

Fingerprint

Neurotoxins
Alanine
Cycasin
Gymnosperms
Neurodegenerative diseases
Glucosides
Neurodegenerative Diseases
beta-N-methylamino-L-alanine
methylazoxymethanol

Keywords

  • Amyotrophic lateral sclerosis
  • Cycas micronesica Hill
  • Cycasin
  • DNA damage
  • Excitotoxin
  • L-BMAA
  • L-BOAA
  • Parkinsonism-dementia complex

ASJC Scopus subject areas

  • Toxicology

Cite this

Cycad β-N-methylamino-L-alanine (BMAA), methylazoxymethanol, genotoxicity, and neurodegeneration. / Spencer, Peter; Palmer, Valerie; Kisby, Glen E.

In: Toxicon, Vol. 155, 01.12.2018, p. 49-50.

Research output: Contribution to journalLetter

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keywords = "Amyotrophic lateral sclerosis, Cycas micronesica Hill, Cycasin, DNA damage, Excitotoxin, L-BMAA, L-BOAA, Parkinsonism-dementia complex",
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KW - DNA damage

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