Cutaneous responses to vaccinia in individuals with previous smallpox vaccination

Eric Simpson, Michelle Hercher, Erika K. Hammarlund, Matthew W. Lewis, Mark Slifka, Jon Hanifin

    Research output: Contribution to journalArticle

    6 Citations (Scopus)

    Abstract

    The durability of immune responses to smallpox vaccine is a subject of considerable debate. We compared cutaneous vaccinia responses in patients vaccinated in the distant past with vaccine-naïve individuals using serial close-up photographs. The previously vaccinated group had a significantly reduced time course and milder cutaneous reactions. Vaccinated individuals appear to maintain clinically detectable immunity against vaccinia for at least 20 years after smallpox vaccination.

    Original languageEnglish (US)
    Pages (from-to)442-444
    Number of pages3
    JournalJournal of the American Academy of Dermatology
    Volume57
    Issue number3
    DOIs
    StatePublished - Sep 2007

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    Vaccinia
    Smallpox
    Vaccination
    Smallpox Vaccine
    Skin
    Immunity
    Vaccines

    ASJC Scopus subject areas

    • Dermatology

    Cite this

    Cutaneous responses to vaccinia in individuals with previous smallpox vaccination. / Simpson, Eric; Hercher, Michelle; Hammarlund, Erika K.; Lewis, Matthew W.; Slifka, Mark; Hanifin, Jon.

    In: Journal of the American Academy of Dermatology, Vol. 57, No. 3, 09.2007, p. 442-444.

    Research output: Contribution to journalArticle

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