Current Smoking as a predictor of chronic musculoskeletal pain in young adult twins

Amy Holley, Emily F. Law, See Wan Tham, Mon Myaing, Carolyn Noonan, Eric Strachan, Tonya M. Palermo

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Chronic pain is common during adolescence and young adulthood and is associated with poor quality of life, depression, and functional disability. Recognizing that chronic pain has significant consequences, it is important to identify modifiable health behaviors that may place young adults at risk for chronic pain. This study examines associations between chronic musculoskeletal pain and smoking in young adult twins (n = 1,588, ages 18-30) participating in a statewide twin registry. Twins completed questionnaires assessing smoking, mood (anxiety, depressive symptoms, and stress), and chronic musculoskeletal pain. Analyses examined associations between chronic pain and smoking, particularly the role of genetics/shared familial factors and psychological symptoms. As predicted, results revealed a near-2-fold increased risk for chronic musculoskeletal pain in twins who currently smoked compared to nonsmokers, even when accounting for psychological factors. Results of within-pair analyses were only minimally attenuated, suggesting that associations between smoking and chronic musculoskeletal pain are better accounted for by nonshared factors than by shared familial factors/genetic effects. Future twin research is needed to identify what nonshared factors (eg, attitudes, direct effects of smoking on pain) contribute to these associations to further understand comorbidity. Longitudinal studies and recruitment of participants prior to smoking initiation and chronic pain onset will better identify causal associations. Perspective: This article describes associations between musculoskeletal pain and smoking in young adult twins, taking into account psychological symptoms. Findings highlight the importance of nonshared factors in associations between pain and smoking and the need to explore the roles of lifestyle, individual attitudes, and direct effects of smoking on pain.

Original languageEnglish (US)
Pages (from-to)1131-1139
Number of pages9
JournalJournal of Pain
Volume14
Issue number10
DOIs
StatePublished - Oct 2013
Externally publishedYes

Fingerprint

Musculoskeletal Pain
Chronic Pain
Young Adult
Smoking
Psychology
Pain
Depression
Health Behavior
Longitudinal Studies
Registries
Life Style
Comorbidity
Anxiety
Quality of Life

Keywords

  • Chronic pain
  • smoking
  • twins
  • young adult

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Neurology
  • Clinical Neurology

Cite this

Holley, A., Law, E. F., Tham, S. W., Myaing, M., Noonan, C., Strachan, E., & Palermo, T. M. (2013). Current Smoking as a predictor of chronic musculoskeletal pain in young adult twins. Journal of Pain, 14(10), 1131-1139. https://doi.org/10.1016/j.jpain.2013.04.012

Current Smoking as a predictor of chronic musculoskeletal pain in young adult twins. / Holley, Amy; Law, Emily F.; Tham, See Wan; Myaing, Mon; Noonan, Carolyn; Strachan, Eric; Palermo, Tonya M.

In: Journal of Pain, Vol. 14, No. 10, 10.2013, p. 1131-1139.

Research output: Contribution to journalArticle

Holley, A, Law, EF, Tham, SW, Myaing, M, Noonan, C, Strachan, E & Palermo, TM 2013, 'Current Smoking as a predictor of chronic musculoskeletal pain in young adult twins', Journal of Pain, vol. 14, no. 10, pp. 1131-1139. https://doi.org/10.1016/j.jpain.2013.04.012
Holley, Amy ; Law, Emily F. ; Tham, See Wan ; Myaing, Mon ; Noonan, Carolyn ; Strachan, Eric ; Palermo, Tonya M. / Current Smoking as a predictor of chronic musculoskeletal pain in young adult twins. In: Journal of Pain. 2013 ; Vol. 14, No. 10. pp. 1131-1139.
@article{159396d74cb940269b51368a606aa210,
title = "Current Smoking as a predictor of chronic musculoskeletal pain in young adult twins",
abstract = "Chronic pain is common during adolescence and young adulthood and is associated with poor quality of life, depression, and functional disability. Recognizing that chronic pain has significant consequences, it is important to identify modifiable health behaviors that may place young adults at risk for chronic pain. This study examines associations between chronic musculoskeletal pain and smoking in young adult twins (n = 1,588, ages 18-30) participating in a statewide twin registry. Twins completed questionnaires assessing smoking, mood (anxiety, depressive symptoms, and stress), and chronic musculoskeletal pain. Analyses examined associations between chronic pain and smoking, particularly the role of genetics/shared familial factors and psychological symptoms. As predicted, results revealed a near-2-fold increased risk for chronic musculoskeletal pain in twins who currently smoked compared to nonsmokers, even when accounting for psychological factors. Results of within-pair analyses were only minimally attenuated, suggesting that associations between smoking and chronic musculoskeletal pain are better accounted for by nonshared factors than by shared familial factors/genetic effects. Future twin research is needed to identify what nonshared factors (eg, attitudes, direct effects of smoking on pain) contribute to these associations to further understand comorbidity. Longitudinal studies and recruitment of participants prior to smoking initiation and chronic pain onset will better identify causal associations. Perspective: This article describes associations between musculoskeletal pain and smoking in young adult twins, taking into account psychological symptoms. Findings highlight the importance of nonshared factors in associations between pain and smoking and the need to explore the roles of lifestyle, individual attitudes, and direct effects of smoking on pain.",
keywords = "Chronic pain, smoking, twins, young adult",
author = "Amy Holley and Law, {Emily F.} and Tham, {See Wan} and Mon Myaing and Carolyn Noonan and Eric Strachan and Palermo, {Tonya M.}",
year = "2013",
month = "10",
doi = "10.1016/j.jpain.2013.04.012",
language = "English (US)",
volume = "14",
pages = "1131--1139",
journal = "Journal of Pain",
issn = "1526-5900",
publisher = "Churchill Livingstone",
number = "10",

}

TY - JOUR

T1 - Current Smoking as a predictor of chronic musculoskeletal pain in young adult twins

AU - Holley, Amy

AU - Law, Emily F.

AU - Tham, See Wan

AU - Myaing, Mon

AU - Noonan, Carolyn

AU - Strachan, Eric

AU - Palermo, Tonya M.

PY - 2013/10

Y1 - 2013/10

N2 - Chronic pain is common during adolescence and young adulthood and is associated with poor quality of life, depression, and functional disability. Recognizing that chronic pain has significant consequences, it is important to identify modifiable health behaviors that may place young adults at risk for chronic pain. This study examines associations between chronic musculoskeletal pain and smoking in young adult twins (n = 1,588, ages 18-30) participating in a statewide twin registry. Twins completed questionnaires assessing smoking, mood (anxiety, depressive symptoms, and stress), and chronic musculoskeletal pain. Analyses examined associations between chronic pain and smoking, particularly the role of genetics/shared familial factors and psychological symptoms. As predicted, results revealed a near-2-fold increased risk for chronic musculoskeletal pain in twins who currently smoked compared to nonsmokers, even when accounting for psychological factors. Results of within-pair analyses were only minimally attenuated, suggesting that associations between smoking and chronic musculoskeletal pain are better accounted for by nonshared factors than by shared familial factors/genetic effects. Future twin research is needed to identify what nonshared factors (eg, attitudes, direct effects of smoking on pain) contribute to these associations to further understand comorbidity. Longitudinal studies and recruitment of participants prior to smoking initiation and chronic pain onset will better identify causal associations. Perspective: This article describes associations between musculoskeletal pain and smoking in young adult twins, taking into account psychological symptoms. Findings highlight the importance of nonshared factors in associations between pain and smoking and the need to explore the roles of lifestyle, individual attitudes, and direct effects of smoking on pain.

AB - Chronic pain is common during adolescence and young adulthood and is associated with poor quality of life, depression, and functional disability. Recognizing that chronic pain has significant consequences, it is important to identify modifiable health behaviors that may place young adults at risk for chronic pain. This study examines associations between chronic musculoskeletal pain and smoking in young adult twins (n = 1,588, ages 18-30) participating in a statewide twin registry. Twins completed questionnaires assessing smoking, mood (anxiety, depressive symptoms, and stress), and chronic musculoskeletal pain. Analyses examined associations between chronic pain and smoking, particularly the role of genetics/shared familial factors and psychological symptoms. As predicted, results revealed a near-2-fold increased risk for chronic musculoskeletal pain in twins who currently smoked compared to nonsmokers, even when accounting for psychological factors. Results of within-pair analyses were only minimally attenuated, suggesting that associations between smoking and chronic musculoskeletal pain are better accounted for by nonshared factors than by shared familial factors/genetic effects. Future twin research is needed to identify what nonshared factors (eg, attitudes, direct effects of smoking on pain) contribute to these associations to further understand comorbidity. Longitudinal studies and recruitment of participants prior to smoking initiation and chronic pain onset will better identify causal associations. Perspective: This article describes associations between musculoskeletal pain and smoking in young adult twins, taking into account psychological symptoms. Findings highlight the importance of nonshared factors in associations between pain and smoking and the need to explore the roles of lifestyle, individual attitudes, and direct effects of smoking on pain.

KW - Chronic pain

KW - smoking

KW - twins

KW - young adult

UR - http://www.scopus.com/inward/record.url?scp=84885019264&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84885019264&partnerID=8YFLogxK

U2 - 10.1016/j.jpain.2013.04.012

DO - 10.1016/j.jpain.2013.04.012

M3 - Article

C2 - 23810151

AN - SCOPUS:84885019264

VL - 14

SP - 1131

EP - 1139

JO - Journal of Pain

JF - Journal of Pain

SN - 1526-5900

IS - 10

ER -