Current controversies in prenatal diagnosis 2: Prediction and prevention of adverse pregnancy outcomes requires a genomic rather than proteomic solution

What's already known about this topic?Adverse pregnancy outcomes associated with placental dysfunction is a leading cause of perinatal morbidity and mortality in the non-malformed fetus/newborn and also of maternal morbidity and mortality.They are also responsible for long-term effects on maternal and child/adult health.They encompass different clinical phenotypes for which the etiopathophysiology is far from being well understood. What does this study add?This study provides a written transcript to accompany an oral debate that was presented at the 18th International Conference on Prenatal Diagnosis and Therapy in Brisbane, Australia, on 22 July 2014.It provides different insights about the potential benefits of different approaches, proteomics, and genomics, in the search for improving our knowledge in placental mediated adverse pregnancy outcomes.