TY - JOUR
T1 - Wernicke's Encephalopathy
AU - Reuler, James B.
AU - Girard, Donald E.
AU - Cooney, Thomas G.
PY - 1985/4/18
Y1 - 1985/4/18
N2 - Despite its description over a century ago, Wernicke's encephalopathy continues to be underrecognized in both alcoholic and nonalcoholic populations. Recent studies suggest that Wernicke's encephalopathy is the most common neuropathological finding underlying chronic cognitive impairment in alcoholics and that its prevalence at autopsy, in both alcoholic and nonalcoholic populations, far exceeds its rate of recognition during life. Since Wernicke's encephalopathy is both treatable and preventable, and untold health care expenditures result from the disorder, familiarity with its epidemiologic and clinical features is important. In this article, the pathophysiologic, clinical, and neuropathological features of Wernicke's encephalopathy are reviewed, and principles of…
AB - Despite its description over a century ago, Wernicke's encephalopathy continues to be underrecognized in both alcoholic and nonalcoholic populations. Recent studies suggest that Wernicke's encephalopathy is the most common neuropathological finding underlying chronic cognitive impairment in alcoholics and that its prevalence at autopsy, in both alcoholic and nonalcoholic populations, far exceeds its rate of recognition during life. Since Wernicke's encephalopathy is both treatable and preventable, and untold health care expenditures result from the disorder, familiarity with its epidemiologic and clinical features is important. In this article, the pathophysiologic, clinical, and neuropathological features of Wernicke's encephalopathy are reviewed, and principles of…
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U2 - 10.1056/NEJM198504183121606
DO - 10.1056/NEJM198504183121606
M3 - Review article
C2 - 3885034
AN - SCOPUS:0021946192
SN - 0028-4793
VL - 312
SP - 1035
EP - 1039
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 16
ER -