Crosslinked shells for nano-assembled capsules

A new encapsulation method for smaller Gd3+-loaded capsules with exceedingly high relaxivities

Annah Farashishiko, Sally E. Plush, Karley B. Maier, A. Dean Sherry, Mark Woods

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Nano-assembled capsules can incorporate large payloads of high relaxivity Gd3+, permitting the development of highly detectable molecular imaging agents for MRI. A new encapsulating shell, based upon cross-linked peptides, is found to afford smaller capsules (127 nm average diameter) with exceptionally high per-Gd3+ relaxivities (70.7 s-1 mmolal-1).

Original languageEnglish (US)
Pages (from-to)6355-6358
Number of pages4
JournalChemical Communications
Volume53
Issue number47
DOIs
StatePublished - 2017

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Molecular imaging
Encapsulation
Magnetic resonance imaging
Peptides
Capsules

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Crosslinked shells for nano-assembled capsules : A new encapsulation method for smaller Gd3+-loaded capsules with exceedingly high relaxivities. / Farashishiko, Annah; Plush, Sally E.; Maier, Karley B.; Dean Sherry, A.; Woods, Mark.

In: Chemical Communications, Vol. 53, No. 47, 2017, p. 6355-6358.

Research output: Contribution to journalArticle

Farashishiko, Annah ; Plush, Sally E. ; Maier, Karley B. ; Dean Sherry, A. ; Woods, Mark. / Crosslinked shells for nano-assembled capsules : A new encapsulation method for smaller Gd3+-loaded capsules with exceedingly high relaxivities. In: Chemical Communications. 2017 ; Vol. 53, No. 47. pp. 6355-6358.
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