Cross-sectional echocardiography in hypoplastic left ventricle: Echocardiographic-angiographic-anatomic correlations

Lothar W. Lange, David J. Sahn, Hugh D. Allen, Theron W. Ovitt, Stanley J. Goldberg

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Although M-mode echocardiography has become a valuable tool in the noninvasive diagnosis of hypoplastic left ventricle (HLV), it may not resolve all diagnostic uncertainty. This study compares the findings of M-mode echocardiography, cross-sectional echocardiography, and autopsy in a group of 20 infants with HLV. M-mode echocardiograms alone were obtained in eight infants; five of these children underwent cardiac catheterization, and six underwent autopsy. Cross-sectional echocardiograms were obtained in the remaining 12 infants; two of these underwent cardiac catheterization, and all 12 underwent autopsy. Cross-sectional examinations were performed with either a high-resolution mechanical sector scanner or a sequentially scanning linear array. Short-axis views were used for left ventricular size and shape and for aortic root, pulmonary artery, and ductus size; suprasternal notch views were used for imaging the aortic arch and subxiphoid views for the atrial cavities. In all 12 infants the findings from cross-sectional echocardiography closely matched those of autopsy with respect to degree of hypoplasia of the mitral valve, the left ventricular cavity, and the left ventricular outflow tract. If the diameter of a valve orifice exceeded 3 mm at autopsy, patency of the valve could be diagnosed from the cross-sectional echocardiogram. The findings when M-mode echocardiograms alone were done less closely matched the autopsy findings, and in five of the eight cardiac catheterization was judged necessary to resolve remaining diagnostic uncertainty. This study found that cross-sectional echocardiography provided an accurate noninvasive diagnosis of the spectrum of anatomy found in HLV and had fewer pitfalls than M-mode echocardiography.

Original languageEnglish (US)
Pages (from-to)287-299
Number of pages13
JournalPediatric Cardiology
Issue number4
StatePublished - Dec 1 1980


  • Echocardiography
  • Hypoplastic left ventricle
  • Noninvasive

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine


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