Critical evaluation of food and mite allergy in the management of atopic dermatitis

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

The subject of allergic causation of atopic dermatitis (AD) has been a source of controversy for over sixty years. While there is general agreement of allergen-induced asthma and allergic rhinoconjunctivitis, AD lesions cannot be readily or consistently induced by foods and inhalants. The most consistent perturbators of atopic conditions are irritants, probably reflecting the consistent inflammatory cell hyper-reactivity due to elevated cyclic AMP-phosphodiesterase activity. The immunologic reactions are another manifestation of that general cellular dysregulation.

Original languageEnglish (US)
Pages (from-to)495-503
Number of pages9
JournalJournal of Dermatology
Volume24
Issue number8
DOIs
StatePublished - Aug 1997

Keywords

  • Allergens
  • Atopic dermatitis
  • Irritants
  • Phosphodiesterase

ASJC Scopus subject areas

  • Dermatology

Fingerprint Dive into the research topics of 'Critical evaluation of food and mite allergy in the management of atopic dermatitis'. Together they form a unique fingerprint.

  • Cite this