CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level

Garmen Yuen, Fehad J. Khan, Shaojian Gao, Jayne M. Stommel, Eric Batchelor, Xiaolin Wu, Ji Luo

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46 Scopus citations

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Medicine & Life Sciences