Coupled light transport-heat diffusion model for laser dosimetiy with dynamic optical properties

Richard A. London; Michael E. Glinsky; George B. Zimmerman; David C. Eder; Steven L. Jacques

doi:10.1117/12.209941

Coupled light transport-heat diffusion model for laser dosimetiy with dynamic optical properties

Richard A. London, Michael E. Glinsky, George B. Zimmerman, David C. Eder, Steven L. Jacques

Biomedical Engineering

Research output: Contribution to journal › Conference article › peer-review

4 Scopus citations

Abstract

The effect of dynamic optical properties on the spatial distribution of light in laser therapy is studied via numerical simulations. A two-dimensional, time dependent computer program called LATIS is used. Laser light transport is simulated with a Monte Carlo technique including anisotropic scattering and absorption. Thermal heat transport is calculated with a finite difference algorithm. Material properties are specified on a 2-D mesh and can be arbitrary functions of space and time. Arrhenius rate equations are solved for tissue damage caused by elevated temperatures. Optical properties are functions of tissue damage, as determined by previous measurements. Results are presented for the time variation of the the light distribution and damage within the tissue as the optical properties of the tissue are altered.

Original language	English (US)
Pages (from-to)	434-442
Number of pages	9
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	2391
DOIs	https://doi.org/10.1117/12.209941
State	Published - May 22 1995
Event	Laser-Tissue Interaction VI 1995 - San Jose, United States Duration: Feb 1 1995 → Feb 8 1995

Keywords

Dynamic optics
Laser dosimetry
Laser-tissue modeling
Tissue damage

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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Coupled light transport-heat diffusion model for laser dosimetiy with dynamic optical properties. / London, Richard A.; Glinsky, Michael E.; Zimmerman, George B.; Eder, David C.; Jacques, Steven L.

In: Proceedings of SPIE - The International Society for Optical Engineering, Vol. 2391, 22.05.1995, p. 434-442.

Research output: Contribution to journal › Conference article › peer-review

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title = "Coupled light transport-heat diffusion model for laser dosimetiy with dynamic optical properties",

abstract = "The effect of dynamic optical properties on the spatial distribution of light in laser therapy is studied via numerical simulations. A two-dimensional, time dependent computer program called LATIS is used. Laser light transport is simulated with a Monte Carlo technique including anisotropic scattering and absorption. Thermal heat transport is calculated with a finite difference algorithm. Material properties are specified on a 2-D mesh and can be arbitrary functions of space and time. Arrhenius rate equations are solved for tissue damage caused by elevated temperatures. Optical properties are functions of tissue damage, as determined by previous measurements. Results are presented for the time variation of the the light distribution and damage within the tissue as the optical properties of the tissue are altered.",

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author = "London, {Richard A.} and Glinsky, {Michael E.} and Zimmerman, {George B.} and Eder, {David C.} and Jacques, {Steven L.}",

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AU - London, Richard A.

AU - Glinsky, Michael E.

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AU - Eder, David C.

AU - Jacques, Steven L.

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AB - The effect of dynamic optical properties on the spatial distribution of light in laser therapy is studied via numerical simulations. A two-dimensional, time dependent computer program called LATIS is used. Laser light transport is simulated with a Monte Carlo technique including anisotropic scattering and absorption. Thermal heat transport is calculated with a finite difference algorithm. Material properties are specified on a 2-D mesh and can be arbitrary functions of space and time. Arrhenius rate equations are solved for tissue damage caused by elevated temperatures. Optical properties are functions of tissue damage, as determined by previous measurements. Results are presented for the time variation of the the light distribution and damage within the tissue as the optical properties of the tissue are altered.

KW - Dynamic optics

KW - Laser dosimetry

KW - Laser-tissue modeling

KW - Tissue damage

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