Corticotropin-releasing hormone-related peptides and receptors: Emergent regulators of cardiovascular adaptations to stress

Sarah C. Coste, Robert F. Quintos, Mary P. Stenzel-Poore

Research output: Contribution to journalReview article

57 Scopus citations

Abstract

Since its discovery 2 decades ago, potent effects of corticotropin-releasing hormone (CRH) on the heart and vasculature have been consistently observed. The recent discoveries of novel CRH-related peptides residing in the heart and a distinct cardiac CRH receptor (CRH-R2), have renewed interest in the role of the CRH family on cardiovascular function. This review highlights the emerging view of a peripheral, cardiac CRH system and its potential relevance in mediating the adaptive response of the heart to stress. (Trends Cardiovascular Med 2002;12:176-182).

Original languageEnglish (US)
Pages (from-to)176-182
Number of pages7
JournalTrends in Cardiovascular Medicine
Volume12
Issue number4
DOIs
StatePublished - Jun 13 2002

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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