Corticotropin releasing factor (CRF) activity in rat plasma

John Kendall, D. K. Gray, N. D. Gaudette

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The ACTH releasing activity of hypothalamic extract and rat plasma was examined with the dispersed rat pituitary cell technique of Swallow and Sayers. Although both plasma and serum caused ACTH release which was dose related, stress did not enhance the ACTH releasing activity. Furthermore, separation studies of plasma using ultrafiltration and gel separation suggest that the CRF activity in plasma is associated with molecules of a molecular weight greater than 15,000.

Original languageEnglish (US)
Pages (from-to)691-694
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume152
Issue number4
StatePublished - 1976
Externally publishedYes

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Corticotropin-Releasing Hormone
Rats
Adrenocorticotropic Hormone
Plasmas
Swallows
Ultrafiltration
Thermodynamic properties
Molecular Weight
Gels
Molecular weight
Molecules
Serum

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Corticotropin releasing factor (CRF) activity in rat plasma. / Kendall, John; Gray, D. K.; Gaudette, N. D.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 152, No. 4, 1976, p. 691-694.

Research output: Contribution to journalArticle

Kendall, John ; Gray, D. K. ; Gaudette, N. D. / Corticotropin releasing factor (CRF) activity in rat plasma. In: Proceedings of the Society for Experimental Biology and Medicine. 1976 ; Vol. 152, No. 4. pp. 691-694.
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