Corrigendum to “RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9” [Food Chem. Toxicol. 134 Supplement 1 2019 110723 ISSN 0278–6915] (Food and Chemical Toxicology (2019) 134(S1), (S0278691519305137), (10.1016/j.fct.2019.110723))

A. M. Api; D. Belsito; D. Botelho; M. Bruze; G. A. Burton; J. Buschmann; M. L. Dagli; M. Date; W. Dekant; C. Deodhar; M. Francis; A. D. Fryer; L. Jones; K. Joshi; S. La Cava; A. Lapczynski; D. C. Liebler; D. O'Brien; A. Patel; T. M. Penning; G. Ritacco; J. Romine; N. Sadekar; D. Salvito; T. W. Schultz; I. G. Sipes; G. Sullivan; Y. Thakkar; Y. Tokura; S. Tsang

doi:10.1016/j.fct.2022.112815

Corrigendum to “RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9” [Food Chem. Toxicol. 134 Supplement 1 2019 110723 ISSN 0278–6915] (Food and Chemical Toxicology (2019) 134(S1), (S0278691519305137), (10.1016/j.fct.2019.110723))

A. M. Api, D. Belsito, D. Botelho, M. Bruze, G. A. Burton, J. Buschmann, M. L. Dagli, M. Date, W. Dekant, C. Deodhar, M. Francis, A. D. Fryer, L. Jones, K. Joshi, S. La Cava, A. Lapczynski, D. C. Liebler, D. O'Brien, A. Patel, T. M. PenningG. Ritacco, J. Romine, N. Sadekar, D. Salvito, T. W. Schultz, I. G. Sipes, G. Sullivan, Y. Thakkar, Y. Tokura, S. Tsang

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

The authors regret that the following paragraph (the first paragraph under “9.1.2. Risk assessment”) was included in error and should be disregarded: “2,2,6-Trimethylcyclohexanone was assessed in the BlueScreen assay and found negative for both cytotoxicity (positive: < 80% relative cell density) and genotoxicity, with and without metabolic activation (RIFM, 2013). BlueScreen is a screening assay that assesses genotoxic stress through alterations in gene expressions in a human cell line. Additional assays were considered to fully assess the potential mutagenic or clastogenic effects of the target material.” The authors would like to apologise for any inconvenience caused.

Original language	English (US)
Article number	112815
Journal	Food and Chemical Toxicology
Volume	161
DOIs	https://doi.org/10.1016/j.fct.2022.112815
State	Published - Mar 2022
Externally published	Yes

ASJC Scopus subject areas

Food Science
Toxicology

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Api, A. M., Belsito, D., Botelho, D., Bruze, M., Burton, G. A., Buschmann, J., Dagli, M. L., Date, M., Dekant, W., Deodhar, C., Francis, M., Fryer, A. D., Jones, L., Joshi, K., La Cava, S., Lapczynski, A., Liebler, D. C., O'Brien, D., Patel, A., ... Tsang, S. (2022). Corrigendum to “RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9” [Food Chem. Toxicol. 134 Supplement 1 2019 110723 ISSN 0278–6915] (Food and Chemical Toxicology (2019) 134(S1), (S0278691519305137), (10.1016/j.fct.2019.110723)). Food and Chemical Toxicology, 161, [112815]. https://doi.org/10.1016/j.fct.2022.112815

Corrigendum to “RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9” [Food Chem. Toxicol. 134 Supplement 1 2019 110723 ISSN 0278–6915] (Food and Chemical Toxicology (2019) 134(S1), (S0278691519305137), (10.1016/j.fct.2019.110723)). / Api, A. M.; Belsito, D.; Botelho, D.; Bruze, M.; Burton, G. A.; Buschmann, J.; Dagli, M. L.; Date, M.; Dekant, W.; Deodhar, C.; Francis, M.; Fryer, A. D.; Jones, L.; Joshi, K.; La Cava, S.; Lapczynski, A.; Liebler, D. C.; O'Brien, D.; Patel, A.; Penning, T. M.; Ritacco, G.; Romine, J.; Sadekar, N.; Salvito, D.; Schultz, T. W.; Sipes, I. G.; Sullivan, G.; Thakkar, Y.; Tokura, Y.; Tsang, S.

In: Food and Chemical Toxicology, Vol. 161, 112815, 03.2022.

Research output: Contribution to journal › Comment/debate › peer-review

Api, AM, Belsito, D, Botelho, D, Bruze, M, Burton, GA, Buschmann, J, Dagli, ML, Date, M, Dekant, W, Deodhar, C, Francis, M, Fryer, AD, Jones, L, Joshi, K, La Cava, S, Lapczynski, A, Liebler, DC, O'Brien, D, Patel, A, Penning, TM, Ritacco, G, Romine, J, Sadekar, N, Salvito, D, Schultz, TW, Sipes, IG, Sullivan, G, Thakkar, Y, Tokura, Y & Tsang, S 2022, 'Corrigendum to “RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9” [Food Chem. Toxicol. 134 Supplement 1 2019 110723 ISSN 0278–6915] (Food and Chemical Toxicology (2019) 134(S1), (S0278691519305137), (10.1016/j.fct.2019.110723))', Food and Chemical Toxicology, vol. 161, 112815. https://doi.org/10.1016/j.fct.2022.112815

Api AM, Belsito D, Botelho D, Bruze M, Burton GA, Buschmann J et al. Corrigendum to “RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9” [Food Chem. Toxicol. 134 Supplement 1 2019 110723 ISSN 0278–6915] (Food and Chemical Toxicology (2019) 134(S1), (S0278691519305137), (10.1016/j.fct.2019.110723)). Food and Chemical Toxicology. 2022 Mar;161. 112815. https://doi.org/10.1016/j.fct.2022.112815

Api, A. M. ; Belsito, D. ; Botelho, D. ; Bruze, M. ; Burton, G. A. ; Buschmann, J. ; Dagli, M. L. ; Date, M. ; Dekant, W. ; Deodhar, C. ; Francis, M. ; Fryer, A. D. ; Jones, L. ; Joshi, K. ; La Cava, S. ; Lapczynski, A. ; Liebler, D. C. ; O'Brien, D. ; Patel, A. ; Penning, T. M. ; Ritacco, G. ; Romine, J. ; Sadekar, N. ; Salvito, D. ; Schultz, T. W. ; Sipes, I. G. ; Sullivan, G. ; Thakkar, Y. ; Tokura, Y. ; Tsang, S. / Corrigendum to “RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9” [Food Chem. Toxicol. 134 Supplement 1 2019 110723 ISSN 0278–6915] (Food and Chemical Toxicology (2019) 134(S1), (S0278691519305137), (10.1016/j.fct.2019.110723)). In: Food and Chemical Toxicology. 2022 ; Vol. 161.

@article{11b8375e5d5d496f825c4e45df2d5d80,

title = "Corrigendum to “RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9” [Food Chem. Toxicol. 134 Supplement 1 2019 110723 ISSN 0278–6915] (Food and Chemical Toxicology (2019) 134(S1), (S0278691519305137), (10.1016/j.fct.2019.110723))",

abstract = "The authors regret that the following paragraph (the first paragraph under “9.1.2. Risk assessment”) was included in error and should be disregarded: “2,2,6-Trimethylcyclohexanone was assessed in the BlueScreen assay and found negative for both cytotoxicity (positive: < 80% relative cell density) and genotoxicity, with and without metabolic activation (RIFM, 2013). BlueScreen is a screening assay that assesses genotoxic stress through alterations in gene expressions in a human cell line. Additional assays were considered to fully assess the potential mutagenic or clastogenic effects of the target material.” The authors would like to apologise for any inconvenience caused.",

author = "Api, {A. M.} and D. Belsito and D. Botelho and M. Bruze and Burton, {G. A.} and J. Buschmann and Dagli, {M. L.} and M. Date and W. Dekant and C. Deodhar and M. Francis and Fryer, {A. D.} and L. Jones and K. Joshi and {La Cava}, S. and A. Lapczynski and Liebler, {D. C.} and D. O'Brien and A. Patel and Penning, {T. M.} and G. Ritacco and J. Romine and N. Sadekar and D. Salvito and Schultz, {T. W.} and Sipes, {I. G.} and G. Sullivan and Y. Thakkar and Y. Tokura and S. Tsang",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Ltd",

year = "2022",

month = mar,

doi = "10.1016/j.fct.2022.112815",

language = "English (US)",

volume = "161",

journal = "Food and Chemical Toxicology",

issn = "0278-6915",

publisher = "Elsevier Limited",

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T1 - Corrigendum to “RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9” [Food Chem. Toxicol. 134 Supplement 1 2019 110723 ISSN 0278–6915] (Food and Chemical Toxicology (2019) 134(S1), (S0278691519305137), (10.1016/j.fct.2019.110723))

AU - Api, A. M.

AU - Belsito, D.

AU - Botelho, D.

AU - Bruze, M.

AU - Burton, G. A.

AU - Buschmann, J.

AU - Dagli, M. L.

AU - Date, M.

AU - Dekant, W.

AU - Deodhar, C.

AU - Francis, M.

AU - Fryer, A. D.

AU - Jones, L.

AU - Joshi, K.

AU - La Cava, S.

AU - Lapczynski, A.

AU - Liebler, D. C.

AU - O'Brien, D.

AU - Patel, A.

AU - Penning, T. M.

AU - Ritacco, G.

AU - Romine, J.

AU - Sadekar, N.

AU - Salvito, D.

AU - Schultz, T. W.

AU - Sipes, I. G.

AU - Sullivan, G.

AU - Thakkar, Y.

AU - Tokura, Y.

AU - Tsang, S.

PY - 2022/3

Y1 - 2022/3

N2 - The authors regret that the following paragraph (the first paragraph under “9.1.2. Risk assessment”) was included in error and should be disregarded: “2,2,6-Trimethylcyclohexanone was assessed in the BlueScreen assay and found negative for both cytotoxicity (positive: < 80% relative cell density) and genotoxicity, with and without metabolic activation (RIFM, 2013). BlueScreen is a screening assay that assesses genotoxic stress through alterations in gene expressions in a human cell line. Additional assays were considered to fully assess the potential mutagenic or clastogenic effects of the target material.” The authors would like to apologise for any inconvenience caused.

AB - The authors regret that the following paragraph (the first paragraph under “9.1.2. Risk assessment”) was included in error and should be disregarded: “2,2,6-Trimethylcyclohexanone was assessed in the BlueScreen assay and found negative for both cytotoxicity (positive: < 80% relative cell density) and genotoxicity, with and without metabolic activation (RIFM, 2013). BlueScreen is a screening assay that assesses genotoxic stress through alterations in gene expressions in a human cell line. Additional assays were considered to fully assess the potential mutagenic or clastogenic effects of the target material.” The authors would like to apologise for any inconvenience caused.

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Corrigendum to “RIFM fragrance ingredient safety assessment, 2,2,6-trimethylcyclohexanone, CAS Registry Number 2408-37-9” [Food Chem. Toxicol. 134 Supplement 1 2019 110723 ISSN 0278–6915] (Food and Chemical Toxicology (2019) 134(S1), (S0278691519305137), (10.1016/j.fct.2019.110723))

Abstract

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