Correlations of Perceived Deficits Questionnaire of multiple sclerosis quality of life inventory with Beck Depression Inventory and neuropsychological tests

Jesus Lovera, Bridget Bagert, Kyle H. Smoot, Katherine Wild, Rachel Frank, Kristin Bogardus, Barry Oken, Ruth Whitham, Dennis Bourdette

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

The Perceived Deficits Questionnaire (PDQ) is a part of the Multiple Sclerosis (MS) Quality of Life Inventory that assesses self-perceived cognitive difficulties. We used baseline data from 49 MS subjects participating in a clinical trial to evaluate the correlation of the PDQ with two measures of cognitive impairment, the Paced Auditory Serial Addition Test (PASAT) and the California Verbal Learning Test, 2nd edition (CVLT-II), total score, and one measure of depression, the Beck Depression Inventory-Amended (BDI-IA). The PDQ correlated significantly (r = 0.42; 95% confidence interval [CI], 0.15 to 0.62; p = 0.003) with the BDI-IA scores but not with either the PASAT (r = - 0.22; 95% CI, - 0.48 to 0.06; p = 0.2) or the CVLT-II total (r = - 0.17; 95% CI, -0.43 to 0.12; p = 0.25). A subset of 38 of these subjects who scored worse than 0.5 standard deviation below the mean on the PASAT or CVLT-II received a more extensive neuropsychological battery of tests. No significant correlations were found between any of these tests and the PDQ. These results suggest that self-perceived cognitive dysfunction relates more to depression than to objective cognitive dysfunction.

Original languageEnglish (US)
Pages (from-to)73-82
Number of pages10
JournalJournal of Rehabilitation Research and Development
Volume43
Issue number1
DOIs
StatePublished - 2006

Fingerprint

Neuropsychological Tests
Verbal Learning
Multiple Sclerosis
Quality of Life
Depression
Equipment and Supplies
Confidence Intervals
Clinical Trials
Surveys and Questionnaires
Cognitive Dysfunction

Keywords

  • Beck Depression Inventory
  • California Verbal Learning Test
  • Cognition disorders
  • Depression
  • Multiple sclerosis
  • Neuropsychological tests
  • Paced Auditory Serial Addition Test
  • Perceived Deficits Questionnaire
  • Quality of life
  • Questionnaires

ASJC Scopus subject areas

  • Rehabilitation
  • Health Professions(all)
  • Engineering(all)

Cite this

@article{4763d40f1ca34e38aafd782132df41a9,
title = "Correlations of Perceived Deficits Questionnaire of multiple sclerosis quality of life inventory with Beck Depression Inventory and neuropsychological tests",
abstract = "The Perceived Deficits Questionnaire (PDQ) is a part of the Multiple Sclerosis (MS) Quality of Life Inventory that assesses self-perceived cognitive difficulties. We used baseline data from 49 MS subjects participating in a clinical trial to evaluate the correlation of the PDQ with two measures of cognitive impairment, the Paced Auditory Serial Addition Test (PASAT) and the California Verbal Learning Test, 2nd edition (CVLT-II), total score, and one measure of depression, the Beck Depression Inventory-Amended (BDI-IA). The PDQ correlated significantly (r = 0.42; 95{\%} confidence interval [CI], 0.15 to 0.62; p = 0.003) with the BDI-IA scores but not with either the PASAT (r = - 0.22; 95{\%} CI, - 0.48 to 0.06; p = 0.2) or the CVLT-II total (r = - 0.17; 95{\%} CI, -0.43 to 0.12; p = 0.25). A subset of 38 of these subjects who scored worse than 0.5 standard deviation below the mean on the PASAT or CVLT-II received a more extensive neuropsychological battery of tests. No significant correlations were found between any of these tests and the PDQ. These results suggest that self-perceived cognitive dysfunction relates more to depression than to objective cognitive dysfunction.",
keywords = "Beck Depression Inventory, California Verbal Learning Test, Cognition disorders, Depression, Multiple sclerosis, Neuropsychological tests, Paced Auditory Serial Addition Test, Perceived Deficits Questionnaire, Quality of life, Questionnaires",
author = "Jesus Lovera and Bridget Bagert and Smoot, {Kyle H.} and Katherine Wild and Rachel Frank and Kristin Bogardus and Barry Oken and Ruth Whitham and Dennis Bourdette",
year = "2006",
doi = "10.1682/JRRD.2004.09.0118",
language = "English (US)",
volume = "43",
pages = "73--82",
journal = "Journal of rehabilitation R&D",
issn = "0007-506X",
publisher = "Department of Veterans Affairs",
number = "1",

}

TY - JOUR

T1 - Correlations of Perceived Deficits Questionnaire of multiple sclerosis quality of life inventory with Beck Depression Inventory and neuropsychological tests

AU - Lovera, Jesus

AU - Bagert, Bridget

AU - Smoot, Kyle H.

AU - Wild, Katherine

AU - Frank, Rachel

AU - Bogardus, Kristin

AU - Oken, Barry

AU - Whitham, Ruth

AU - Bourdette, Dennis

PY - 2006

Y1 - 2006

N2 - The Perceived Deficits Questionnaire (PDQ) is a part of the Multiple Sclerosis (MS) Quality of Life Inventory that assesses self-perceived cognitive difficulties. We used baseline data from 49 MS subjects participating in a clinical trial to evaluate the correlation of the PDQ with two measures of cognitive impairment, the Paced Auditory Serial Addition Test (PASAT) and the California Verbal Learning Test, 2nd edition (CVLT-II), total score, and one measure of depression, the Beck Depression Inventory-Amended (BDI-IA). The PDQ correlated significantly (r = 0.42; 95% confidence interval [CI], 0.15 to 0.62; p = 0.003) with the BDI-IA scores but not with either the PASAT (r = - 0.22; 95% CI, - 0.48 to 0.06; p = 0.2) or the CVLT-II total (r = - 0.17; 95% CI, -0.43 to 0.12; p = 0.25). A subset of 38 of these subjects who scored worse than 0.5 standard deviation below the mean on the PASAT or CVLT-II received a more extensive neuropsychological battery of tests. No significant correlations were found between any of these tests and the PDQ. These results suggest that self-perceived cognitive dysfunction relates more to depression than to objective cognitive dysfunction.

AB - The Perceived Deficits Questionnaire (PDQ) is a part of the Multiple Sclerosis (MS) Quality of Life Inventory that assesses self-perceived cognitive difficulties. We used baseline data from 49 MS subjects participating in a clinical trial to evaluate the correlation of the PDQ with two measures of cognitive impairment, the Paced Auditory Serial Addition Test (PASAT) and the California Verbal Learning Test, 2nd edition (CVLT-II), total score, and one measure of depression, the Beck Depression Inventory-Amended (BDI-IA). The PDQ correlated significantly (r = 0.42; 95% confidence interval [CI], 0.15 to 0.62; p = 0.003) with the BDI-IA scores but not with either the PASAT (r = - 0.22; 95% CI, - 0.48 to 0.06; p = 0.2) or the CVLT-II total (r = - 0.17; 95% CI, -0.43 to 0.12; p = 0.25). A subset of 38 of these subjects who scored worse than 0.5 standard deviation below the mean on the PASAT or CVLT-II received a more extensive neuropsychological battery of tests. No significant correlations were found between any of these tests and the PDQ. These results suggest that self-perceived cognitive dysfunction relates more to depression than to objective cognitive dysfunction.

KW - Beck Depression Inventory

KW - California Verbal Learning Test

KW - Cognition disorders

KW - Depression

KW - Multiple sclerosis

KW - Neuropsychological tests

KW - Paced Auditory Serial Addition Test

KW - Perceived Deficits Questionnaire

KW - Quality of life

KW - Questionnaires

UR - http://www.scopus.com/inward/record.url?scp=33745315405&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33745315405&partnerID=8YFLogxK

U2 - 10.1682/JRRD.2004.09.0118

DO - 10.1682/JRRD.2004.09.0118

M3 - Article

C2 - 16847773

AN - SCOPUS:33745315405

VL - 43

SP - 73

EP - 82

JO - Journal of rehabilitation R&D

JF - Journal of rehabilitation R&D

SN - 0007-506X

IS - 1

ER -