Correlation of static speckle with sample properties in optical coherence tomography

Timothy R. Hillman, Steven G. Adie, Volker Seemann, Julian J. Armstrong, Steven L. Jacques, David D. Sampson

Research output: Contribution to journalArticle

50 Scopus citations

Abstract

We present theoretical calculations, based on a random phasor sum model, which show that the optical coherence tomography speckle contrast ratio is dependent on the local density of scattering particles in a sample, provided that the effective number of scatterers in the probed volume is less than about five. We confirm these theoretical predictions experimentally, using suspensions of microspheres in water. The observed contrast ratios vary in value from the Rayleigh limit of 0.52 to in excess of 2, suggesting that the contrast ratio could be useful in optical coherence tomography, particularly when imaging in ultrahigh-resolution regimes.

Original languageEnglish (US)
Pages (from-to)190-192
Number of pages3
JournalOptics Letters
Volume31
Issue number2
DOIs
StatePublished - Jan 15 2006

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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    Hillman, T. R., Adie, S. G., Seemann, V., Armstrong, J. J., Jacques, S. L., & Sampson, D. D. (2006). Correlation of static speckle with sample properties in optical coherence tomography. Optics Letters, 31(2), 190-192. https://doi.org/10.1364/OL.31.000190